Toshio Sugahara

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To analyze the lip movement of patients with cleft lip and palate in detail, we developed a novel technique to produce a range image from a video-based motion capture system, and a unique technique to analyze lip movements in detail three-dimensionally. The accuracy of the range image obtained from the present system was investigated using a positioning(More)
The appearance of the nostril in cleft lip patients is very important in the subjective assessment of naso-labial forms and patient satisfaction. To improve the outcome of plastic surgery, a computer aided diagnostic system was developed. Facial forms were measured with a three-dimensional optical scanner (Ogis Range Finder RFX-IV) XYZ coordinates (256x240)(More)
Background: The chondrosarcoma-derived HCS-2/8 has been known to be an excellent model of human articular chondrocytes. By mimicking the arthritic conditions through the treatment of HCS-2/8 cells with cytokines, we estimated the gene expression response of ccn1 and ccn2 during the course of joint inflammation in vitro.
OBJECTIVE To evaluate the motion of the face and jaw of patients with cleft lip and palate, facial palsy, and in patients after reconstruction, a motion-analyzing system was developed. The aim of this article was to investigate the accuracy of this system and the possibility of clinical application. METHODS Markers of 1 to 2 mm were placed on the face,(More)
To quantify the shape of cleft lip noses and to evaluate the outcome following rhinoplasty objectively, a three-dimensional measuring system for the nasal shape was developed using a contact-type measuring apparatus. In this system, the surface data for a face could be obtained accurately, and facial landmarks could be identified semiautomatically. A new(More)
OBJECTIVES The aim of the present study was to determine whether there are dialectal and gender-related differences in nasalance scores for normal Japanese speakers. MATERIALS Sixty-eight volunteers consisting of 31 males (age 23.8+/-2.0) and 37 females (age 23.2+/-2.5) were included in this study. They had no diseases affecting speech, and lived in the(More)
The palatal forms in 20 infants with a complete unilateral cleft lip, and palate (12 with a Hotz palate and 8 without, selected at random) were studied from birth until 18 months of age. Using techniques developed previously, the degree of curvature in the palate and the magnitude of migration of the maxillary segments were measured three-dimensionally.(More)
Palatogenesis is directed by epithelial-mesenchymal interactions and results partly from remodeling of the extracellular matrix (ECM) of the palatal shelves. Here, we assessed heparanase distribution in developing mouse palates. No heparanase was observed in the vertically oriented palatal shelves in early stages of palate formation. As palate formation(More)
OBJECTIVES The aim of this study was to apply a novel method to the analysis of lip motion in patients with bilateral cleft lip and palate before and after lip repair with cross-lip flaps, and to compare lip motion between the patients and healthy volunteers. METHODS Two 17-year-old bilateral cleft lip patients (one male and one female) who underwent lip(More)