Toshio Moriya

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SPHIRE (SPARX for High-Resolution Electron Microscopy) is a novel open-source, user-friendly software suite for the semi-automated processing of single particle electron cryo-microscopy (cryo-EM) data. The protocol presented here describes in detail how to obtain a near-atomic resolution structure starting from cryo-EM micrograph movies by guiding users(More)
Mitsugumin 23 (MG23) is a 23 kDa transmembrane protein localized to the sarcoplasmic/endoplasmic reticulum and nuclear membranes in a wide variety of cells. Although the characteristics imply the participation in a fundamental function in intracellular membrane systems, the physiological role of MG23 is unknown. Here we report the biochemical and(More)
We describe the geometrical properties of solid's shadows projected onto a flat plane by point-light sources. Even though the shape and position of each element are arbitrary and unknown, we indicate that there exists a certain constraint between three shadows on the plane; i.e., three cross points determined by pairs of tangential lines must sit on a(More)
We present a method of surface reconstruction from high-density scatter points P = {p1, p2, ..., pN} without a normal vector in R3. This method first sets a uniform grid and deforms each cell of the grid by fitting the vertex of each cell to the nearest of the input points. It then constructs triangles according to the pattern of the vertices’s state in(More)
We introduce a new environment to make and play interactive contents with more than video game quality. The system consists of a projector array, a viewer and an editor for the special contents. The projector array projects multiple digital images seamlessly both in time and space, thus a very high quality video projection system. The viewer features a(More)
The Sec translocon facilitates transportation of newly synthesized polypeptides from the cytoplasm to the lumen/periplasm across the phospholipid membrane. Although the polypeptide-conducting machinery is formed by the SecYEG-SecA complex in bacteria, its transportation efficiency is markedly enhanced by SecDF. A previous study suggested that SecDF assumes(More)