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  • M Jane Cox Rosemond, Lisa St John-Williams, Toshiro Yamaguchi, Toshio Fujishita, John S. Walsh
  • Chemistry, Medicine
  • Chemico-biological interactions
  • 1 March 2004
  • S-1360, a 1,3-diketone derivative, was the first HIV integrase inhibitor to enter human trials. Clinical data suggested involvement of non-cytochrome P450 clearance pathways, including reduction andContinue Reading