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We conducted a community-based interview survey of a random sample of residents aged 20 years or older in an urban community in Japan using the University of Michigan Version of the WHO Composite International Diagnostic Interview for selected mood and anxiety disorders and alcohol abuse/dependence according to DSM-III-R. The final sample consisted of 1029(More)
The psychometric properties of the Japanese Test of Self-Conscious Affect-3 (TOSCA-3), a self-report measure of self-conscious emotions, were examined in Japanese university students. Confirmatory factor analyses showed good fits of the theory-driven model for 6 emotions to the data. The subscales of the TOSCA-3 showed moderate correlations and internal(More)
A retrospective study of negative sexual experiences (NSEs) was conducted among 532 Japanese university women. More than one third of the respondents reported having experienced at least one NSE, and two thirds were victimized by strangers. When the woman knew the perpetrator well, the NSE was more likely to be repeated. One sixth of victims did not(More)
BACKGROUND Unexplained miscarriage is speculated to be due to a Th1/Th2 cytokine imbalance at the feto-maternal interface and immunological functions are known to be under the influence of various psychological factors. Indeed, the psycho-neuro-immuno-endocrine network has been proposed to contribute to miscarriage. To assess whether psychological disorders(More)
Advanced glycation end products (AGE) are known to serve as ligands for the scavenger receptors such as SR-A, CD36 and SR-BI. In the current study, we examined whether AGE is recognized by lectin-like oxidized low density lipoprotein receptor-1 (LOX-1). Cellular binding experiments revealed that AGE-bovine serum albumin (AGE-BSA) showed the specific binding(More)
The authors conducted in-depth interviews with 38 mothers and fathers who had lost an infant. The focus of the interview was aggression and guilt during mourning work. The participants felt strong shame after separation. Phenomena such as strong irrational guilt, aggression, and hesitation toward others were similar to feelings typical of the(More)
OBJECTIVE The Temperament and Character Inventory (TCI) is a widely used self-report measure of adult personality. METHOD We studied 586 Japanese university and college students with the 125-item version of the Japanese TCI. RESULTS The factor structure of the TCI scales was similar to that reported in other languages. Depression was positively(More)
The first well-documented outbreak of acute methyl mercury (MeHg) poisoning by consumption of contaminated fish occurred in Minamata, Japan, in 1953. The clinical picture was officially recognized and called Minamata disease (MD) in 1956. However, 50 years later there are still arguments about the definition of MD in terms of clinical symptoms and extent of(More)
Previous studies from our laboratory demonstrated that N(epsilon)-(carboxymethyl)lysine (CML), one of the major advanced glycation end products (AGE), was accumulated in human pyramidal neurons in the hippocampus in an age-dependent manner. This suggests a potential link between AGE-accumulation and the aging process in neurons. The purpose of the present(More)