Toshimutsu Fujii

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The incidence of hot flashes under hormone manipulation therapy is so high that this symptom caused by sex hormone blocking agents has been bothering patients and has a negative impact on their quality of life. Venlafaxine and gabapentin are most promising novel nonestrogenic agents to control the symptom. We seek to quatitatively summarize the efficacy of(More)
Helicobacter pylori a gram negative bacilli is related with development of gastroduodenal disease as chronic active gastritis, peptic ulcer disease MALT type lymphomas and gastric cancer. The WHO defined H. pylori as a human carcinogen agent. Helicobacter colonizes the gastric epithelium and promotes inflammation and mucosal damage. Third part of the(More)
Ulcerative colitis (UC) and Crohn's disease (CD) is an inflammatory bowel disease of unknown aetiology characterized by periods of remission and acute episodes of relapse with severe inflammation in the colonic mucosa. Conventional treatments for UC and CD include 5-aminosalicylate, corticosteroid, elemental dietary treatment, corticosteroid, and thiopurine(More)