Toshiko Nakai

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BACKGROUND Consistent detection of rotor(s) and/or focal impulse(s) of atrial fibrillation can using a 64-pole basket catheter remain unclear. METHODS AND RESULTS Intracardiac left atrial electrograms were recorded, prior to ablation, in 20 patients with atrial fibrillation. Unipolar electrograms, filtered at 0.1-300 Hz, were recorded and exported for an(More)
BACKGROUND Although alteration of the amplitude and morphology of bipolar electrograms is used widely as a guide of the ablation effect, there is little information concerning unipolar electrograms. The amplitude and morphology of filtered bipolar (BP) and filtered unipolar (UP) electrograms were compared during pulmonary vein isolation in patients with(More)
BACKGROUND Complex fractionated atrial electrograms (CFAEs) and high dominant frequency (DF) are targets for atrial fibrillation (AF) ablation. Although adenosine triphosphate (ATP) is known to promote AF by shortening the atrial refractory period, its role in the pathogenesis of CFAEs and DF during AF is not fully understood. METHODS We recorded(More)
BACKGROUND Because obesity is an important risk factor for atrial fibrillation (AF), we conducted an animal study to examine the effect of a high-fat diet (HFD) on atrial properties and AF inducibility. METHODS Ten 8-week-old pigs (weight, 18-23 kg) were divided into two groups. For 18 weeks, five pigs were fed a HFD (HFD group) and five were fed a normal(More)
After a morphometric analysis of nerve fibers of the human recurrent laryngeal nerve, which is connected with phonation, the authors discovered several changes occurring in the axon during the aging process. These changes are mainly the disappearance of large axons and a slenderization of all remaining axons. This is the first time that such observation has(More)
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