Toshiki Yokoyama

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Expressed emotion (EE) is the attitude of criticism and emotional overinvolvement of a key relative toward a patient, and is one of the family factors that contribute to the course of psychiatric illness. The relationship between EE and 6-month outcome in 40 outpatients with major depression was investigated in this study. In the nonremission group (n = 17,(More)
10 Meuwissen R, Linn SC, Linnoila RI, et al. Induction of small cell lung cancer by somatic inactivation of both Trp53 and Rb1 in a conditional mouse model. Autoimmune pancreatitis (AIP) is characterised by a high serum immunoglobulin (Ig)G4 concentration and various extrapancreatic complications, including those of the lung [1]. Therefore, AIP is currently(More)
Autoimmune pancreatitis is a unique form of chronic pancreatitis characterised by a high-serum immunoglobulin (Ig)G4 concentration involving various extra pancreatic lesions. A 63-yr-old female with autoimmune pancreatitis complained of cough. Chest computed tomography revealed an irregular stenosis of the central airway, lung hilar and mediastinal lymph(More)
BACKGROUND Lung-dominant connective tissue disease (LD-CTD) is a new concept for classifying the subset of patients with interstitial pneumonia who have clinical features suggesting an associated CTD, but whose features fall short of a clear diagnosis of CTD under the current rheumatologic classification systems. The impact of mean pulmonary arterial(More)
We investigated the relationship between 9-month relapse of 40 outpatients with schizophrenia and expressed emotion (EE) evaluated by the Five-Minute Speech Sample (FMSS). The results of this study suggest that the FMSS is suitable for use as a convenient instrument to measure EE, although it shows more false-positive results. Therefore borderline EE of the(More)
A Projected effects of tobacco smoking on worldwide tuberculosis control: mathematical modelling analysis. BMJ 2011; 343: d5506. 5 Van Rie A, Patel MR, Nana M Integration and task-shifting for TB/HIV care and treatment in highly resource-scarce settings: one size may not fit all. Risk factors for default from tuberculosis treatment in HIV-infected(More)
A 54-year-old man was admitted to our hospital for further examination following a chest radiographic screening test. He was asymptomatic but had an elevated serum concentration of alpha-fetoprotein. Chest computed tomography (CT) and magnetic resonance imaging showed a posterior mediastinal mass in the left thoracic paravertebral region. CT-guided(More)
Based on randomized controlled trials conducted in western countries, we proposed a pharmacotherapy algorithm for DSM-IV dysthymia in Japan. The main strategy of the algorithm are: firstly, one of the antidepressants is selected for an initial agent, and secondly, efficacy of the selected antidepressant is evaluated at 8 to 12 weeks. The agent with(More)
Expressed emotion (EE) has been shown in various countries to be a good predictor of the clinical course of a patient's mental illness. Because the traditional EE interview requires considerable time and effort, this study examined the reliability of a method called the five-minute speech sample (FMSS) for assessing EE. The samples of 65 subjects were rated(More)
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