Toshiki Ohya

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Degenerative changes of intrahepatic bile ducts with lymphocytic infiltration into portal areas have been recognized as the characteristic histopathologic features in the liver with biliary atresia (BA). Occasionally, lymphocytic infiltration into biliary ductal epithelium was noted and has been thought to be mostly the result of nonspecific chronic(More)
The excretion of D-glucaric acid (DGA), a metabolite of the cytochrome P-450 pathway, is considered a marker of the viability of hepatocytes. Twelve cases of biliary atresia (BA) have been investigated, correlating the level of DGA, degree of histological alteration of liver parenchyma, and clinical outcome. Urine was collected in the preoperative period.(More)
The aim of this study was to evaluate the effects of a traditional Chinese herbal medicine, dai-kenchu-to (DKT), on obstructive bowel diseases in children. We have treated 46 pediatric patients with various obstructive bowel diseases with DKT: six patients with postoperative ileus, 12 with large abdominal surgery (including three neonates), one with(More)
Although the prognosis of biliary atresia has greatly advanced, only two thirds of patients are able to survive for a long time. This study was designed to investigate the correlation between liver fibrosis, size of ductuli at porta hepatis, and prognosis in order to determine the indications for the Kasai operation. The results of this study showed that(More)
BACKGROUND Non-operative management for patients with fistula-in-ano in infancy using a traditional herbal medicine Ginseng and Tang-kuei Ten Combination (GTTC) is described. METHODS A total of 22 patients with peri-anal abscess or fistula-in-ano were treated with GTTC. Eighteen patients showed no improvement using the conventional non-operative(More)
In laparoscopic surgery, surgeons perform surgery in the abdominal cavity by using only slender instruments that can be inserted through small diameter trocars. When it is difficult to perform surgery by using only instruments for laparoscopic surgery, they often make a 7-8 cm incision through which their hand can be inserted. Clearly this is invasive(More)
In laparoscopic surgery large instruments cannot be used because they cannot pass through trocars which are typically smaller than 12mm in diameter. For example, retracting an internal organ with a slender instrument is often a difficult task. To remove this limitation, we have proposed “assemblable instruments”, that is, parts are inserted(More)
Hepatic portoenterostomy (Kasai operation) for the patient with biliary atresia (BA) can restore the bile flow in approximately 80% of children operated on before 60 days of life [1]. However, in terms of long-term survival, according to a recent nationwide survey among the major pediatric centers in Japan, only 325 of 2013 patients had more than 10 years'(More)