Toshihiro Sakamoto

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We report that the light-activated bovine metarhodopsin II, upon decay, first forms opsin in the correctly folded form. The latter binds 11-cis-retinal and regenerates the native rhodopsin chromophore. However, when the opsin formed upon metarhodopsin II decay is kept in 0.1% dodecyl maltoside, it converts in a time-dependent manner to a form(s) that does(More)
a r t i c l e i n f o A crop yield estimation model using time-series MODIS WDRVI was developed. The main feature of the proposed model is the incorporation of crop phenology detection using MODIS data, called the " Shape-Model Fitting Method ". MODIS WDRVI taken 7–10 days before the corn silking stage had strong linear correlation with corn final grain(More)
[1] Water column stratification increased at climatic transitions from cold to warm periods during the late Quaternary and led to anoxic conditions and sapropel formation in the deep eastern Mediterranean basins. High-resolution data sets on sea-surface temperatures (SST) (estimated from U 37 k 0 indices) and d 18 O of planktonic foraminifer calcite (d 18 O(More)
In this study, an inexpensive camera-observation system called the Crop Phenology Recording System (CPRS), which consists of a standard digital color camera (RGB cam) and a modified near-infrared (NIR) digital camera (NIR cam), was applied to estimate green leaf area index (LAI), total LAI, green leaf biomass and total dry biomass of stalks and leaves of(More)
statistics district level. In particular, the annual changes in the spatiotemporal patterns of the estimated silking stage had a high level of agreement with those of the NASS-derived statistics. These results suggested that the TSF method could provide local-scale information of corn phenological stages, which had an advantage over the NASS-derived(More)
We developed a crop scheduling model for rice cultivation in the Vietnam Mekong Delta (VMD), focusing on the adaptive behavior of crop planning to various water resource constraints. In addition, we also examined the effects of environmental change on rice cultivation in the last decade. In the VMD, multiple rice cropping is practiced under a variety of(More)
In migration analysis of the brown planthopper, Nilaparvata lugens (Stål), in a tropical region, it is difficult to know the arrival timing of the immigrants because rice plants in different growth stages are simultaneously cultivated, and local insects may already occur in destination areas. Due to this analytical difficulty, additional information is(More)
A series of trans-3-oxospiro[(aza)isobenzofuran-1(3H),1'-cyclohexane]-4'-carboxamide derivatives were synthesized and profiled for NPY Y5 binding affinity, brain and CSF penetrability in rats, and susceptibility to human and mouse P-glycoprotein transporters in order to develop a PET ligand. Compound 12b exhibited an acceptable profile for a PET ligand, and(More)
We have developed and characterized [(35)S]4a as a potent and selective radioligand for melanin-concentrating hormone 1-receptor (MCH1R). Compound [(35)S]4a showed appreciable specific signals in brain slices prepared from wild-type mice but not from MCH1R deficient mice, confirming the specificity and utility of [(35)S]4a as a selective MCH1R radioligand(More)