Toshihiko Ono

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BACKGROUND Patients with diabetic nephropathy are likely to have neurological complications including cardiovascular autonomic dysfunction, which is related to increased risk of mortality. We investigated whether cardiovascular autonomic neuropathy is associated with left ventricular hypertrophy (LVH) in diabetic haemodialysis patients. METHODS Holter(More)
PURPOSE We investigated whether impaired patterns of myocardial fatty acid imaging were associated with cardiac death in dialysis patients without coronary lesions. METHODS We prospectively enrolled 155 hemodialysis patients without obstructive coronary artery disease, who had been examined by single-photon emission computed tomography (SPECT) using the(More)
BACKGROUND S100A12 is an endogenous ligand of the receptor for advanced glycation end products (RAGE). Plasma S100A12 levels are high in end-stage renal disease (ESRD) patients undergoing maintenance hemodialysis (HD). Peripheral arterial disease (PAD) is common in HD patients and is associated with increased cardiovascular morbidity and mortality rates in(More)
We investigated whether chronic intravenous administration of l-carnitine could improve myocardial fatty acid imaging in patients on maintenance hemodialysis. We enrolled 72 hemodialysis patients who had impaired myocardial fatty acid imaging and left ventricular dysfunction not based on coronary lesion. l-Carnitine (1,000 mg) was intravenously administered(More)
This letter proposes a new scenario to solve the structural or conceptual problems remained in quantum mechanics, and gives an overview of the theory proposed in quant-ph/9906130 (including quant-ph/9909025 and quant-ph/0001015). Although quantum mechanics in twentieth century has succeeded to predict the correct results of large numbers of experiments in(More)
This paper proves that protomechanics, previously introduced in quant-ph/9909025, deduces both quantum mechanics and classical mechanics. It does not only solve the problem of the arbitrariness on the operator ordering for the quantization procedure, but also that of the analyticity at the exact classical-limit of ¯ h = 0. In addition, proto-mechanics(More)
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