Toshihiko Okada

Learn More
We recently found that chemokine-driven peritoneal cell aggregation is the primary mechanism of postoperative adhesion in a mouse model. To investigate this in humans, paired samples of peritoneal lavage fluid were obtained from seven patients immediately after incision (preoperative) and before closure (postoperative), and were assayed for the presence of(More)
Chemokine (C-C motif) receptor 8 (CCR8), the chemokine receptor for chemokine (C-C motif) ligand 1 (CCL1), is expressed in T-helper type-2 lymphocytes and peritoneal macrophages (PMφ) and is involved in various pathological conditions, including peritoneal adhesions. However, the role of CCR8 in inflammatory responses is not fully elucidated. To investigate(More)
UMEROUS thymineless mutants of E. coli, Salmonella, and other bacteria N can be obtained by the aminopterin and thymine method (AM-T method) However, in order to sustain normal growth, all the thymineless mutants thus obtained require ten to 20 times the concentration of thymine required by E. coli 15 T-(COHEN and BARNER 1954). Similar observations were(More)
  • 1