The results of recent research on our implantable CMOS biomedical devices are reviewed. Topics include retinal prosthesis devices and deep-brain implantation devices for small animals. Fundamental device structures and characteristics as well as in vivo experiments are presented.
A complementary metal-oxide semiconductor (CMOS)-based multichip flexible neural stimulator for retinal prostheses was developed. The multichip retinal stimulator is capable of simultaneous multisite stimulation. An on-chip stimulation generator was implemented on the "unit chip," which is the core device of the multichip retinal stimulator. The performance… (More)
In this review, the concept, design, performance, and a functional demonstration of multifunctional complementary metal-oxide-semiconductor (CMOS) image sensors dedicated to on-chip biosensing applications are described. We developed a sensor architecture that allows flexible configuration of a sensing pixel array consisting of optical and electric sensing… (More)
Measurement of brain activity in multiple areas simultaneously by minimally invasive methods contributes to the study of neuroscience and development of brain machine interfaces. However, this requires compact wearable instruments that do not inhibit natural movements. Application of optical potentiometry with voltage-sensitive fluorescent dye using an… (More)
Techniques for fast, noninvasive measurement of neuronal excitability within a broad area will be of major importance for analyzing and understanding neuronal networks and animal behavior in neuroscience field. In this research, a novel implantable imaging system for fluorescence potentiometry was developed using a complementary metal-oxide semiconductor… (More)
| W e discuss articial computer-based KANSEI and its application in a media database retrieval system. In our three-step approach, we rst design a psychological space in which h uman impressions of images , movies, or music are expressed as coordinates. Second, we determine the mapping relationship between the psychological space and physical media… (More)
SUMMARY We review recently obtained results for CMOS (Complementary Metal Oxide Semiconductor) imaging devices used in biomedical applications. The topics include dish type image sensors, deep-brain im-plantation devices for small animals, and retinal prosthesis devices. Fundamental device structures and their characteristics are described, and the results… (More)