Toshie Ogasawara

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We report on a patient who developed primary position upbeat nystagmus (ppUBN) due to a unilateral medial medullary infarction. On oculography, the slow phases of the nystagmus sometimes had an exponentially decreasing velocity waveform, indicating that the nystagmus was due to impairment of the vertical position-to-velocity neural integrator. On magnetic(More)
Event-related potentials (ERPs) were recorded during a mental rotation task that required subjects to determine whether two stimuli presented in turn had the same shape regardless of any difference in orientation. This task consisted of two conditions: the control condition, when the two stimuli presented were identical, requiring only recognition, and the(More)
Behavioural changes in rats two weeks after inescapable shock stress were studied using a shuttle-box task (active avoidance/escape). Rats exposed to inescapable shock stress two weeks beforehand showed more frequent avoidance responses and greater within-group variation in both avoidance response and general activity during the test than rats in a control(More)
The membrane potential was about --50mV, and the spontaneous membrane activity was composed of an irregular discharge of action potentials in the longitudinal muscle of the ovariectomized rat uterus. The membrane potential was increased slightly, and repetitive spike potentials were generated on a plateau potential in uteri of ovariectomized rats injected(More)
We immunized five different strains of mice with the recombinant human PCD17 protein, which is recognized by anti-Purkinje cell antibodies in the sera of patients with paraneoplastic cerebellar degeneration, and explored whether or not antibodies against cerebellar Purkinje cells could be induced in vivo. Autoantibodies against the cytoplasmic protein of(More)
A rare case of neurinoma in a 72 year-old Japanese woman derived from the hypoglossal nerve is reported. The tumour was composed of three interconnected nodules occurring simultaneously in the left submandibular and sublingual regions. The lesion, which presented as a neck mass, caused a slight left-sided hemiparesis of the tongue with tongue deviation to(More)
A 52-kd neural antigen was reported to be recognized by anti-Purkinje cell antibodies in serum of a patient with paraneoplastic cerebellar degeneration associated with uterine carcinoma. In this study, we demonstrate that this neural antigen is recognized by antibodies known as anti-Purkinje cell antibody type I (PCAb Type I) and anti-YO. The latter's(More)
Ovariectomized rats were given one-shot injections of 10 microgram estradiol-17 beta benzoate, and the longitudinal muscle of the uterus was used for experiment 4 days later. The membrane potential was 58.8 +/- 2.4 mV, and the membrane activity consisted of repetitive spike potentials carried on a plateau potential. Oxytocin (1 mU/ml) caused a(More)
A 68-year old woman came to our hospital with a severe case of anemia. Serum immunoelectropheresis identified a monoclonal immunoglobulin (Ig) G and κ protein. The serum IgE level was within the nomal range and the amounts of remaining immunogloblins were low. On bone marrow aspirate, plasma cells made up 55.5% of nucleated cells and the plasma cells showed(More)
In vivo brain microdialysis was used to investigate the role of D3 receptors relating to dopamine auto-regulated systems in the rat. A local infusion of the dopamine D3 selective agonist, 7-OH-DPAT (100 nM), into the striatum through the dialysis membrane produced a significant decrease in extracellular concentrations of dopamine. A local application of(More)