Toshide H. Yosida

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Frequencies of the acrocentric and subtelocentric polymorphism in pairs no. 1, 9 and 13 chromosomes have been examined in 358 black rats, Rattus rattus, distributed over several countries of Asia, Australia and United States. The black rats are divided into three geographical types by the different chromosome numbers, such as Asian (2n=42), Ceylon (2n=40)(More)
The soft-furred rat, Millardia meltada, has bred successfully in the laboratory for 10 generations of brother x sister mating. It is half way in size between the rat and the mouse, and is gentle and easy to handle. Thin body hair and incisor teeth are present in the newborn. Some individuals have low blood pressure. Chromosome number (2n) in 50. It differs(More)
Lung infection with Angiostrongylus cantonensis was established in experimentally infected Indian soft-furred rats (Millardia meltada) and Indian spiny mice (Mus platythrix). Pulmonary arterial migration occurred earlier (at day 20 after infection) in M. meltada than in Wistar rats. M. meltada and M. platythrix could serve as useful animal models for(More)
Chinese hamster D-6 cells were grown for two cell cycles. The effect of 5-bromodeoxyuridine (BrdU) on the frequencies of sister-chromatid exchanges (SCEs) in these cells was investigated by the BrdU-labeling method. A low concentration (5 microM) of BrdU was inoculated in the first cell cycle for SCE counting. When excess concentrations (100-1000 microM) of(More)
Cytogenetical technique newly developed for the observation of chromosomes, such as differential staining of sister-chromatids the high-resolution banding and in situ molecular hybridization are introduced in this chapter. In the differential sister-chromatid staining, acricine-orange, BUdR and FPG techniques are described. In the high resolution banding,(More)
Techniques for the karyotype analysis in the man and some laboratory animals are described in the present chapter. The international systems for the representation of the standard karyotypes in these materials due to the conventional and the several banding stainings are also introduced.
Cytogenetical techniques of the observation of chromosomes in mammals (human) by the cultivation of the peripheral blood cells and also cells suspending in the amniotic fluid are described in this paper. In the blood cell cultivations, the common technique by use of the leukocytes and also a small amount of the whole blood are introduced. The culture(More)
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