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  • Noriyuki Matsuda, Toshiaki Kitami, Toshiaki Suzuki, Yoshikuni Mizuno, Nobutaka Hattori, Keiji Tanaka
  • Biology, Medicine
  • Journal of Biological Chemistry
  • 2006 (First Publication: 10 February 2006)
  • Mutational dysfunction of PARKIN gene, which encodes a double RING finger protein and has ubiquitin ligase E3 activity, is the major cause of autosomal recessive juvenile Parkinsonism. Although manyExpand
  • N Hattori, Hideki Shimura, +8 authors Yoshikuni Mizuno
  • Biology, Medicine
  • Neuropathology : official journal of the Japanese…
  • 2000 (First Publication: 1 September 2000)
  • The contribution of genetic factors to the pathogenesis of Parkinson's disease (PD) is supported by the demonstration of the high concordance in twins studies using positron emission tomographyExpand