Toru Imamura

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OBJECTIVE To elucidate the characteristics of oldest-old patients with dementia in a Japanese memory clinic. METHODS We evaluated 365 consecutive patients with dementia who were referred to the Memory Clinic of Niigata Rehabilitation Hospital, Niigata, Japan over 4-year period. More than 85% of the patients lived in the communities within 15 km from the(More)
Patients rarely experience visual hallucinations while being observed by clinicians. Therefore, instruments to detect visual hallucinations directly from patients are needed. Pareidolias, which are complex visual illusions involving ambiguous forms that are perceived as meaningful objects, are analogous to visual hallucinations and have the potential to be(More)
BACKGROUND/AIMS To identify risk factors for falls in community-dwelling patients with Alzheimer's disease (AD) and dementia with Lewy bodies (DLB). PATIENTS 78 consecutive patients (51 AD, 27 DLB) were recruited from the Niigata Rehabilitation Hospital memory clinic. METHODS We assessed the number of falls each patient had had in the previous 4 months.(More)
BACKGROUND/AIMS Behavioral and psychological symptoms of dementia (BPSD) are common in the clinical manifestation of dementia. Although most patients with dementia exhibit some BPSD during the course of the illness, the association of BPSD with the stage of dementia remains unclear. It was the aim of this study to evaluate the impact of severity of dementia(More)
BACKGROUND/AIMS Our aim was to identify cognitive factors affecting free recall, cued recall, and recognition tasks in patients with Alzheimer's disease (AD). SUBJECTS We recruited 349 consecutive AD patients who attended a memory clinic. METHODS Each patient was assessed using the Alzheimer's Disease Assessment Scale (ADAS) and the extended 3-word(More)
BACKGROUND/AIM Mutations in MAPT cause frontotemporal dementia with parkinsonism linked to chromosome 17 (FTDP-17). Patients with the MAPT R406W mutation were reported to show phenotypic heterogeneity in different ethnic backgrounds. We here report the clinical and genetic characteristics of Japanese families with the R406W mutation. METHODS We examined(More)
Behavioral and psychological symptoms of dementia (BPSD) includes anxiety, depression, hallucination, delusion, aggression, irritability, agitation and wandering. BPSD often causes a deterioration of activity of daily living (ADL) and worsens caregiver burden. Trazodone, an atypical antidepressant, is used for the treatment of BPSD, but the effectiveness is(More)
A 58-year-old right-handed man presented with a 9-year history of stereotyped behaviors and auditory hallucinations. At 49 years of age, he began to complain about auditory hallucinations that said offensive things about him, and around the same time, he began exhibiting stereotyped behaviors. For example, he traveled the same long route from his office to(More)
OBJECTIVE To assess the validity of the short sleep-disorder questionnaire for dementia with Lewy bodies (SDQ-DLB). SDQ-DLB is a newly developed structured interview containing 10 items for assessing REM sleep behavior disorder (RBD) in DLB. SUBJECTS The subjects were 23 patients with a clinical diagnosis of Alzheimer's disease (AD), 21 patients with(More)
Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is an autoimmune disorder, which occurs commonly in young women and is often associated with ovarian teratomas. We report the case of a patient with this disease, who exhibited cognitive deficits, and describe the clinical course of recovery from cognitive dysfunction. A 29-year-old right-handed woman(More)
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