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BACKGROUND Studies on major depressive disorder (MDD) show that the degree of correlation between the Beck Depression Inventory (BDI) and Hamilton Depression Rating Scale (HAMD) varies widely. We aimed to determine whether this discrepancy reflects specific functional abnormalities in the frontotemporal cortex. METHODS Mildly depressed or euthymic(More)
This study aimed to determine whether quality of life (QOL) reflects specific functional abnormalities of frontotemporal hemodynamic responses in melancholia. We recruited 30 patients with major depressive disorder (MDD) with melancholic features (MDD-MF), 52 with non-melancholic features (MDD-NMF), and 68 healthy control subjects who were matched for age,(More)
The aim of this study was to determine whether melancholia differs from nonmelancholic depression in frontotemporal functioning by means of multichannel near-infrared spectroscopy. We recruited 32 major depressive disorder (MDD) patients with melancholic features (MDD-MF), 28 MDD patients with nonmelancholic features (MDD-NMF), and 24 healthy controls.(More)
BACKGROUND Neuroimaging studies using multichannel near-infrared spectroscopy (NIRS) have provided compelling evidence about the dysfunction of the frontotemporal cortices in patients with bipolar disorder (BD). However, it remains unclear whether the dysfunction is associated with mood state or symptom severity. Using NIRS, we aimed to clarify differences(More)
Previous neuroimaging studies have revealed frontal and temporal functional abnormalities in patients with major depressive disorder (MDD) and a history of suicidal behavior. However, it is unknown whether multi-channel near-infrared spectroscopy (NIRS) signal changes among individuals with MDD are associated with a history of suicide attempts and a(More)
ISUAL spectrophotometer and Duke magnetometer observed clear optical and radio signatures of 12 sprite-producing lightning events. In 10 of these, 777.4-nm luminosity normalized to a distance of 3000 km was almost linearly correlated with current moment with a scaling factor of $0.82 MR/kAkm. This finding provides a possible new way to remotely measure(More)
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