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Checkpoints that limit stem cell self-renewal in response to DNA damage can contribute to cancer protection but may also promote tissue aging. Molecular components that control stem cell responses to DNA damage remain to be delineated. Using in vivo RNAi screens, we identified basic leucine zipper transcription factor, ATF-like (BATF) as a major component(More)
This paper delivers an example of applying intelligent data analysis to biological data where the success of the project was only possible due to joint efforts of the experts from biology, medicine and data analysis. The initial and seemingly obvious approach for the analysis of the data yielded results that did not look plausible to the biologists and(More)
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