Torgeir Vegge

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Direct administration of cyclic-AMP into the anterior chamber increases the outflow facility of the eye for aqueous humor. This is consistent with the hypothesis that catecholamines lower the intraocular pressure of the rabbit eye, at least in part, by a cyclic-AMP-mediated mechanism. This mechanism is active in the outflow channels and increases the rate(More)
  • Torgeir Vegge
  • Zeitschrift für Zellforschung und Mikroskopische…
  • 1971
Vervet monkeys were given horseradish peroxidase intravenously. Subsequent studies with the electron microscope showed: 1. The peroxidase molecules penetrated the capillary walls of the ciliary processes and “filled” the stroma and the intercellular spaces as far as the basal junctional complex of the superficial epithelial cells. 2. The ciliary channels(More)
  • Torgeir Vegge
  • Zeitschrift für Zellforschung und Mikroskopische…
  • 1971
Anesthetized vervets were given intravenous injections of horseradish peroxidase. Subsequent studies of iris capillaries with the electron microscope showed peroxidase reaction product within the lumen of the vessels and in endothelial vesicles, but no peroxidase had penetrated the vascular endothelium. The normal ultrastructure of the vascular wall was(More)
Three patients with granular corneal dystrophy Groenouw type I underwent corneal grafting, and cryostat sections of the corneal buttons were examined immunohistochemically for immunoglobulins. Positive results were obtained for IgG, Kappa-, and Lambda chains with immunofluorescence technique. The reactions were seen exclusively in the same localizations as(More)
Albino guinea pigs were given intradermal injections of the protein tracer horseradish peroxidase. In a 0.1 mM concentration the tracer did not increase vascular permeability to Evans blue-labelled plasma proteins. In a 1 mM concentration, however, the peroxidase induced a local vascular leakage. This leakage was almost totally inhibited by pretreating the(More)
The topical application of prostaglandin E2 (dinoprostone) is followed by massive swelling of the ciliary process, leading to substantial leakage of marker dye into the posterior chamber and directly into the region of the iris, where the primary ciliary processes insert. In contrast, blood vessels of the iris proper retain most of their normal barrier(More)
  • Torgeir Vegge
  • Zeitschrift für Zellforschung und Mikroskopische…
  • 1972
Sectors of anterior segments of vervet eyes were exposed to solutions of different osmolarities (Cercopithecus aethiops). After hypertonic incubation followed by isotonic fixation, as well as after fixation directly in hypertonic fixative, the ciliary epithelium showed constant changes. These changes consisted of a shrinkage pattern with dilations of(More)
Protaglandin E2, administered topically to the rabbit eye, causes disruption of the blood-aqueous barrier resulting in a large increase in the protein content of the aqueous humor. The route of plasma proteins into the aqueous humor was studied with the electron microscope, using horseradish peroxidase as a protein tracer. The tracer penetrated the tight(More)
1. The walls of iris vessels in five human eyes were studied. 2. No fenestrae are present in capillary endothelium. 3. A several thousand Å thick basement membrane is found in practically all vessels. The basement membrane is often multi-layered and its external limit irregular. 4. A distinct zone of thin collagen fibrils is present between the “inner” and(More)
The intercellular junctions of the corneal endothelium has been studied in rabbit, monkey and human eyes. A union of apposing outer leaflets (tight junction) is usually found near the apical end of the intercellular clefts. However, evidence from lanthanum tracer studies indicates that the tight junctions do not seal the intercellular clefts completely. In(More)