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  • Xiao-ying Hua, Camilla I. Svensson, Tomohiro Matsui, Bethany L Fitzsimmons, Tony L. Yaksh, Michael Webb
  • Medicine
  • The European journal of neuroscience
  • 2005 (First Publication: 1 November 2005)
  • Activation of p38 mitogen-activated protein kinase (p38) in spinal microglia is implicated in spinal nociceptive processing. Minocycline, a tetracycline derivative, displays selective inhibition ofContinue Reading
  • Sandra R. Chaplan, Annika B. Malmberg, Tony L. Yaksh
  • Medicine
  • The Journal of pharmacology and experimental…
  • 1997 (First Publication: 1 February 1997)
  • Neuropathic pain remains a significant clinical problem. Current understanding implicates the spinal cord dorsal horn N-methyl-d-aspartate (NMDA) receptor apparatus in its pathogenesis. PreviousContinue Reading
  • Maria Schäfers, Doo Hyun Lee, Dominik Brors, Tony L. Yaksh, Linda S. Sorkin
  • Biology, Medicine
  • The Journal of Neuroscience
  • 2003 (First Publication: 1 April 2003)
  • Tumor necrosis factor-α (TNF) is upregulated after nerve injury, causes pain on injection, and its blockade reduces pain behavior resulting from nerve injury; thus it is strongly implicated inContinue Reading
  • Qinghao Xu, Bethany Fitzsimmons, +4 authors Tony L. Yaksh
  • Biology, Medicine
  • The Journal of Neuroscience
  • 2011 (First Publication: 9 February 2011)
  • Phosphinositide 3-kinase (PI3K), Akt, and their downstream kinase, mammalian target of rapamycin (mTOR), are implicated in neural plasticity. The functional linkages of this signaling cascade inContinue Reading
  • Camilla I. Svensson, Martin Marsala, +8 authors Tony L. Yaksh
  • Medicine, Biology
  • Journal of neurochemistry
  • 2003 (First Publication: 21 August 2003)
  • We examined the effect of p38 mitogen-activated protein kinase (MAPK) inhibitors in models of nociception and correlated this effect with localization and expression levels of p38 MAPK in spinalContinue Reading