Toni-Moi N Prince

Learn More
Sleep deprivation disrupts hippocampal function and plasticity. In particular, long-term memory consolidation is impaired by sleep deprivation, suggesting that a specific critical period exists following learning during which sleep is necessary. To elucidate the impact of sleep deprivation on long-term memory consolidation and synaptic plasticity, long-term(More)
Hippocampal cellular and molecular processes critical for memory consolidation are affected by the amount and quality of sleep attained. Questions remain with regard to how sleep enhances memory, what parameters of sleep after learning are optimal for memory consolidation, and what underlying hippocampal molecular players are targeted by sleep deprivation(More)
Social memory was investigated in the context of a spatial working memory task. Pairs of rats were tested in an eight-arm radial maze. Under most conditions, there was a tendency to choose maze locations that had been visited earlier by the other rat. The possibility that this tendency is produced by common preferences for particular maze locations was(More)
iv ACKNOWLEDGEMENT This accomplishment would not have been possible without the dedication and support of many people. First, I would like to thank my advisor, Donald G. Stein, not only for his guidance and assistance with this project, but for providing the chance for me to complete my graduate career in a research area that makes a difference to the(More)
  • 1