Tongling Li

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A simple HPLC method using UV detection was developed and validated for the determination of levodropropizine (LDP) in dog plasma. The sample was prepared for injection using a liquid-liquid extraction method with 1-phenypiperazine as the internal standard. The mobile phase was methanol-diethylamine solution (0.05 M) (20:80, v/v, pH adjusted to 3.0 with(More)
OBJECTIVE To make better the RP-HPLC method with column-switching technique for the determination of salbutamol in human plasma. METHODS A high-pressure flow channel selection valve and Kromasil C18 pretreatment column (20 x 4 mm, 5 microns), Ultrasphere Cyano analysis column (250 mm x 4.6 mm, 5 um, Beckman) were used. To the plasma sample 1.0 ml, 0.5 ml(More)
The relative bioavailability of roxithromycin dispersive tablet in healthy volunteers was evaluated in this study. Its concentration in plasma was detected by high performance liquid chromatography (HPLC) after twenty healthy male volunteers were given each a single dose of 300 mg roxithromycin. The experiment data were obtained using DAS programme. The(More)
OBJECTIVE To study the pharmacokinetics and relative bioavailability of KC-404 sustained release tablets and capsules in healthy volunteers. METHODS The concentration of KC-404 in serum was determined by HPLC method after a single oral dose (20 mg) of tablet or capsule was administered to 19 healthy male volunteers respectively in an open randomized(More)
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