Tong-bao Liu

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OBJECTIVE To identify the genetic variants of angiotensin I converting enzyme 2 (ACE2) gene in a Chinese population and to determine whether the ACE2 gene polymorphisms are associated with essential hypertension (EH). METHODS Seven hundred and forty-five patients with EH and 362 normal blood pressure controls were included in the study to assess the(More)
OBJECTIVE To investigate the effects of atorvastatin on expressions of scavenger receptor A and secretion of monocyte chemoattractant protein-1 (MCP-1) in foam cells. METHODS THP-1 cells were induced to differentiate into macrophages by PMA and treated with 0.1% BSA (control), ox-LDL (100 mg/L) or ox-LDL plus atorvastatin (5, 10, 20 micromol/L) for 24(More)
OBJECTIVE To identify the genetic variants of angiotensin II type 1 receptor (AT1) gene in a population of Han ethnicity in east China and to determine whether the AT1 gene polymorphisms are associated with essential hypertension (EH) and coronary heart disease (CHD). METHODS The detection of single nucleotide polymorphisms (SNPs) was performed in 20(More)
OBJECTIVE To identify single nucleotide polymorphisms (SNP) of the angiotensin II type 2 receptor (AGTR2) gene, and to determine whether the AGTR2 polymorphisms are associated with essential hypertension in a male Chinese population. METHODS Direct DNA sequencing was performed in 20 subjects. 96 male hypertensive patients and 107 normal controls were(More)
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