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Handbook of Signal Processing Systems provides a standalone, complete reference to signal processing systems organized in four parts. The first part motivates representative applications that drive and apply state‐of‐ the art methods for design and implementation of signal processing systems; the second part discusses architectures for implementing these(More)
—In the past few years, Gallager's Low-Density Parity-Check (LDPC) codes received a lot of attention and many efforts have been devoted to analyze and improve their error-correcting performance. However, little consideration has been given to the LDPC decoder VLSI implementation. The straightforward fully parallel decoder architecture usually incurs too(More)
— This paper investigates the potential of using strong BCH codes to improve multilevel data-storage NAND Flash memory capacity. Current multilevel Flash memories store 2 bits in each cell. Further storage capacity may be achieved by increasing the number of storage levels per cell, which nevertheless will largely degrade the raw storage reliability. Based(More)
Targeting on the future fault-prone hybrid CMOS/nanodevice digital memories, this paper presents two fault tolerance design approaches that integrally address the tolerance for defects and transient faults. The first approach is straightforward and easy to implement but suffers from a rapid drop of achievable storage capacity as defect densities and/or(More)
BACKGROUND Characteristics of the human neonatal immune system are thought to be responsible for heightened susceptibility to infectious pathogens and poor responses to vaccine antigens. Using cord blood as a source of immune cells, many reports indicate that the response of neonatal monocytes and dendritic cells (DC) to Toll-like receptor (TLR) agonists(More)
Acute activation of calcium/calmodulin-dependent protein kinase (CaMKII) in permeabilized phospholamban knockout (PLN-KO) mouse myocytes phosphorylates ryanodine receptors (RyRs) and activates spontaneous local sarcoplasmic reticulum (SR) Ca release events (Ca sparks) even at constant SR Ca load. To assess how CaMKII regulates SR Ca release in intact(More)
BACKGROUND Increasing evidence shows that Human Papillomavirus (HPV) is preferentially associated with some head and neck squamous cell carcinomas (HNSCCs), with variable infection rates reported. METHODS We assessed HPV involvement in HNSCC using the Roche Linear Array HPV Genotyping Test, which can detect 37 different HPV types. We examined the(More)
Gallager's Low-Density Parity-Check (LDPC) codes have recently received a lot of attention because of their excellent performance. The decoder hardware implementation is obviously one of the most crucial issues determining the extent of LDPC applications in the real world. The straightforward fully parallel decoder architecture usually incurs too high(More)
BACKGROUND The Notch signalling pathway has been implicated in tumour initiation, progression, angiogenesis and development of resistance to vascular endothelial growth factor (VEGF) targeting, providing a rationale for the combination of RO4929097, a γ-secretase inhibitor, and cediranib, a VEGF receptor tyrosine kinase inhibitor. METHODS Patients(More)