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Epizootiologic survey for Babesia microti among small wild mammals in northeastern Eurasia and a geographic diversity in the beta-tubulin gene sequences.
Findings suggest that U.S-type B. microti is widely distributed among small wild mammals in temperate zones of not only North America, but also Eurasia, whereas that Hobetsu- and Kobe-type parasites may be uniquely distributed in Japan. Expand
Genetic polymorphism of merozoite surface protein-1 and merozoite surface protein-2 in Plasmodium falciparum field isolates from Myanmar
Diverse allelic polymorphism of MSP-1 and Msp-2 was identified in P. falciparum field isolates from Myanmar and most of the infections were determined to be mixed infections, as was a high degree of multiplicity of infection. Expand
Genetic polymorphism in pvmdr1 and pvcrt-o genes in relation to in vitro drug susceptibility of Plasmodium vivax isolates from malaria-endemic countries.
In Korean isolates polymorphism as limited to the F1076L variant, and no isolates with high level of resistance were found by in vitro susceptibility determinations, which provide a baseline for future prospective drug studies in malaria-endemic areas. Expand
Prevalence of cryptosporidiosis among the villagers and domestic animals in several rural areas of Korea.
It was revealed that cryptosporidiosis was an endemic disease in some rural areas of Korea, and the livestock could be an important source of human infection. Expand
First Case of Human Babesiosis in Korea: Detection and Characterization of a Novel Type of Babesia sp. (KO1) Similar to Ovine Babesia
The present study provides the first evidence of the presence of a hitherto unidentified, new type of Babesia parasite capable of infecting humans. Expand
High frequency of genetic diversity of Plasmodium vivax field isolates in Myanmar.
The results collectively suggest that the P. vivax population in Myanmar is highly diverse and multiple clonal infections are prevalent in the country. Expand
Mutations in the antifolate-resistance-associated genes dihydrofolate reductase and dihydropteroate synthase in Plasmodium vivax isolates from malaria-endemic countries.
  • Feng Lu, C. Lim, +8 authors E. Han
  • Biology, Medicine
  • The American journal of tropical medicine and…
  • 1 September 2010
Findings suggests that the prevalence of mutations in pVDhfr and pvdhps in P. vivax isolates from different malaria-endemic countries is associated with selection pressure imposed by sulfadoxine-pyrimethamine. Expand
Genetic polymorphism and natural selection of Duffy binding protein of Plasmodium vivax Myanmar isolates
PvDBPII of Myanmar P. vivax isolates displays a high level of genetic polymorphism and is under selective pressure, useful for understanding the nature of the P.vivax population in Myanmar and for development of PvDBP II-based vaccine. Expand
Developmental Transcriptomic Features of the Carcinogenic Liver Fluke, Clonorchis sinensis
The transcriptomic information on essential regulators of development, bile chemotaxis, and physico-metabolic pathways in C. sinensis that presented in this study will guide further studies to identify novel drug targets and diagnostic antigens. Expand
Genetic variations of the dihydrofolate reductase gene of Plasmodium vivax in Mandalay Division, Myanmar
The results suggest that antifolate-resistant P. vivax is becoming widespread in Myanmar, as it also is in the neighboring countries in Southeast Asia, and appears that the drug resistance situation may be worsening in the country. Expand