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OBJECTIVE To approach the efficiency and feasibility of preserving the fertility for patients with placental site trophoblastic tumor (PSTT). METHODS Totally 2 086 cases of gestational trophoblastic neoplasm (GTN) patients registered in Peking Union Medical College Hospital between 1998 and 2013. Fifty-seven of them were PSTT patients, 40 cases of which(More)
It is reported that membrane-bound form of CX3CL1/fractalkine (FKN) promotes cell-cell adhesion by binding with its unique receptor CX3CR1, and membrane fractalkine works as an adhesion molecule for the communication between tumor cells and vascular endothelial cells. Here, we show that CX3CL1/fractalkine was expressed on both mouse and human solid tumors,(More)
OBJECTIVE To investigate the role of pre-chemotherapy hemoglobin and platelet levels in the effect of chemotherapy and prognostic outcome in patients with International Federation of Gynecology and Obstetrics (FIGO) stage Ib2-IIb cervical cancer treated with neoadjuvant chemotherapy followed by radical hysterectomy. METHODS From January 1999 to December(More)
The optimal treatment for patients with brain metastasis from gestational trophoblastic neoplasia (GTN) has not been established. This study aims to investigate the clinical characteristics and the management of brain metastasis from GTN in relation to patients’ outcomes. We retrospectively investigated 109 GTN patients with brain metastasis treated at(More)
OBJECTIVE The aim of the study was to investigate the clinical manifestations, diagnosis, treatment, and prognosis of primitive neuroectodermal tumors (PNETs) in the female genital tract. METHODS From April 2001 to May 2013, the clinicopathologic characteristics, treatments, outcomes, and prognosis of 11 patients with PNET in the female genital tract were(More)
OBJECTIVE To compare the efficiency and safety of the transperitoneal approaches with retroperitoneal approaches in laparoscopic partial nephrectomy for renal cell carcinoma and provide evidence-based medicine support for clinical treatment. METHODS A systematic computer search of PUBMED, EMBASE, and the Cochrane Library was executed to identify(More)
OBJECTIVE To compare efficacy and safety of laparoscopicnephrectomy (LN) versus open nephrectomy (ON) in the management of autosomal dominant polycystic kidney disease (ADPKD), we conducted a systematic review and meta-analysis. METHODS A systematic search of the electronic databases PubMed, Scopus, and the Cochrane Library was performed up to October(More)
OBJECTIVE To explore the feasibility and value of intra-operative contrast-enhanced ultrasound in different pathological grades of glioma. METHODS A total of 46 patients with glioma were selected to undergo the contrast-enhanced ultrasound. They were divided into 3 groups according to their pathological grades. RESULTS All 46 tumors were hyperechoic(More)
This is the first part of a three-part paper onNorthAmerican climate in phase 5 of theCoupledModel Intercomparison Project (CMIP5) that evaluates the historical simulations of continental and regional climatology with a focus on a core set of 17 models. The authors evaluate themodels for a set of basic surface climate and hydrological variables and their(More)
The present study aimed to examine the potential inhibitory activity of oleoylethanolamide (OEA) on α-melanocyte stimulating hormone (α-MSH)-stimulated melanogenesis and the molecular mechanism(s) involved in the process in B16 mouse melanoma cells. Our data demonstrated that OEA markedly inhibited melanin synthesis and tyrosinase activity in(More)