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Different Inhibitory Effect and Mechanism of Hydroxyapatite Nanoparticles on Normal Cells and Cancer Cells In Vitro and In Vivo
Hydroxyapatite (HAP), similar to inorganic phase in bones, shows good biocompatibility and bioactivity as bone defect repairing material. Recently, nanoscaled HAP shows the special properties… Expand
Enhanced Resolution of DNA Separation Using Agarose Gel Electrophoresis Doped with Graphene Oxide
- Jialiang Li, Y. Yang, Z. Mao, Wenjie Huang, Tong Qiu, Q. Wu
- Materials Science, Medicine
- Nanoscale Research Letters
- 15 September 2016
In this work, a novel agarose gel electrophoresis strategy has been developed for separation of DNA fragments by doping graphene oxide (GO) into agarose gel. The results show that the addition of GO… Expand
PDLLA/PRGD/β-TCP conduits build the neurotrophin-rich microenvironment suppressing the oxidative stress and promoting the sciatic nerve regeneration.
- Tong Qiu, Yixia Yin, +5 authors Shipu Li
- Materials Science, Medicine
- Journal of biomedical materials research. Part A
- 1 October 2014
A novel nerve guidance conduit comprising poly{(lactic acid)-co-[(glycolic acid)-alt-(l-lysine)]} (PRGD), poly (d,l-lactic acid) (PDLLA) and β-tricalcium phosphate (β-TCP) was constructed to… Expand
Influences of surface coatings and components of FePt nanoparticles on the suppression of glioma cell proliferation
- Haiming Sun, Xiaohui Chen, +8 authors Shipu Li
- Materials Science, Medicine
- International journal of nanomedicine
- 6 July 2012
Malignant gliomas are primary brain tumors with high rates of morbidity and mortality; they are the fourth most common cause of cancer death. Novel diagnostic and therapeutic techniques based on… Expand
Tumor-targeted delivery of Silibinin and IPI-549 synergistically inhibit breast cancer by remodeling the microenvironment.
- Min Jiang, Kaiyong He, +4 authors Hua Zheng
- Medicine
- International journal of pharmaceutics
- 16 March 2020
We induced changes in the tumor microenvironment (TME) through the synergistic actions of two drugs used in breast cancer therapy. The anti-fibrotic drug silibinin (SLB) targets tumor-associated… Expand
CdS QDs-chitosan microcapsules with stimuli-responsive property generated by gas-liquid microfluidic technique.
- Y. Chen, Rongyi Yao, Y. Wang, M. Chen, Tong Qiu, Chengyong Zhang
- Materials Science, Medicine
- Colloids and surfaces. B, Biointerfaces
- 2015
This article describes a straightforward gas-liquid microfluidic approach to generate uniform-sized chitosan microcapsules containing CdS quantum dots (QDs). CdS QDs are encapsulated into the… Expand
Redox Sensitive Shell and Core Crosslinked Hyaluronic Acid Nanocarriers for Tumor-Targeted Drug Delivery.
- Hua Zheng, Liangquan Yin, +6 authors Q. Wang
- Medicine, Materials Science
- Journal of biomedical nanotechnology
- 1 August 2016
The purpose of the present study was to develop a robust and redox-sensitive nanocarrier based on amphiphilic hyaluronic acid nanoparticles, in which the hydrophobic core was crosslinked by… Expand
A pH-Sensitive Nanosystem Based on Carboxymethyl Chitosan for Tumor-Targeted Delivery of Daunorubicin.
- X. Zhang, H. Zhang, +6 authors Q. Wang
- Medicine, Materials Science
- Journal of biomedical nanotechnology
- 1 August 2016
Nanoparticles, such as polymeric micelles, are currently regarded as effective drug delivery vehicles. In this study, a series of carboxymethyl chitosan/daunorubicin (CMCS/DNR) conjugates with… Expand
Cisplatin-crosslinked glutathione-sensitive micelles loaded with doxorubicin for combination and targeted therapy of tumors.
The delivery of combination chemotherapy by nanoscale platforms has been demonstrated to enhance cancer treatment in the clinic. Cisplatin (CDDP)-crosslinked, glutathione-sensitive, tumor-targeting… Expand
CORRIGENDUM: Different Inhibitory Effect and Mechanism of Hydroxyapatite Nanoparticles on Normal Cells and Cancer Cells In Vitro and In Vivo
Hydroxyapatite (HAP), similar to inorganic phase in bones, shows good biocompatibility and bioactivity as bone defect repairing material. Recently, nanoscaled HAP shows the special properties… Expand
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