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Animal models of atherosclerosis
Different species of atherosclerosis models are outlined, with discussions on the practicality of their use for experimentation, and their advantages and disadvantages. Expand
Autonomic Nerve Stimulation Reverses Ventricular Repolarization Sequence in Rabbit Hearts
It is demonstrated that bilateral autonomic activity (SNS or vagus nerve stimulation) cause reversible shifts of apex–base DOR and that the spatial heterogeneities of autonomic effects on the ventricles are most likely attributable to a greater innervation at the base than the apex of the heart. Expand
Association between C-reactive protein and recurrence of atrial fibrillation after successful electrical cardioversion: a meta-analysis.
- Tong Liu, G. Li, Li-jian Li, P. Korantzopoulos
- Journal of the American College of Cardiology
- 17 April 2007
The meta-analysis suggests that increased CRP levels are associated with greater risk of AF recurrence, although there was significant heterogeneity across the studies. Expand
Empagliflozin, a sodium glucose co-transporter-2 inhibitor, alleviates atrial remodeling and improves mitochondrial function in high-fat diet/streptozotocin-induced diabetic rats
Empagliflozin can ameliorate atrial structural and electrical remodeling as well as improve mitochondrial function and mitochondrial biogenesis in T2DM, hence may be potentially used in the prevention of T2 DM-related atrial fibrillation. Expand
Meta-analysis of Fragmented QRS as an Electrocardiographic Predictor for Arrhythmic Events in Patients with Brugada Syndrome
It was showed that BrS patients with fQRS are at high risk for future arrhythmic events, and the presence of f QRS warrants prospective evaluation as valid arrhythmogenic risk marker in BrS. Expand
Current Understanding of the Pathophysiology of Myocardial Fibrosis and Its Quantitative Assessment in Heart Failure
This review summarizes the current knowledge regarding the pathophysiology, quantitative assessment, and novel therapeutic strategies of myocardial fibrosis. Expand
Probucol Prevents Atrial Remodeling by Inhibiting Oxidative Stress and TNF‐α/NF‐κB/TGF‐β Signal Transduction Pathway in Alloxan‐Induced Diabetic Rabbits
Diabetes mellitus (DM) is an independent risk factor for atrial fibrillation (AF). However, the underlying mechanisms for the increased propensity for AF in the setting of DM and the potential… Expand
Systematic review and meta-analysis of chronic kidney disease as predictor of atrial fibrillation recurrence following catheter ablation.
A meta-analysis of 4 observational studies showed that CKD was associated with higher AF recurrence rate following single catheter ablation, and patients with 100% paroxysmal AF have higher risk than patients with non 100%Paroxys mal AF that merits special consideration when evaluating patients for catheter-based AF ablation. Expand
Association between angiotensin-converting enzyme insertion/deletion gene polymorphism and atrial fibrillation: a meta-analysis.
- Tong Liu, P. Korantzopoulos, +4 authors Guangping Li
- Europace : European pacing, arrhythmias, and…
- 1 March 2011
A meta-analysis of relevant studies suggests that there is insufficient evidence to demonstrate an association between ACE I/D polymorphism and AF risk, however, there seems to be a significant association betweenACE I-D gene polymorphic variation and AF in patients with hypertension. Expand
Diabetes mellitus and atrial fibrillation: Pathophysiological mechanisms and potential upstream therapies.
- C. Goudis, P. Korantzopoulos, I. Ntalas, E. Kallergis, Tong Liu, D. Ketikoglou
- International journal of cardiology
- 1 April 2015
The present review highlights the association between DM and AF, provides a comprehensive overview of the responsible pathophysiological mechanisms and briefly discusses potential upstream therapies for DM-related atrial remodeling. Expand