Tonatiuh Peña Centeno

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In this paper we consider a novel Bayesian interpretation of Fisher’s discriminant analysis. We relate Rayleigh’s coefficient to a noise model that minimises a cost based on the most probable class centres and that abandons the ‘regression to the labels’ assumption used by other algorithms. Optimisation of the noise model yields a direction of(More)
Despite high heritability of schizophrenia, genome-wide association studies (GWAS) have not yet revealed distinct combinations of single-nucleotide polymorphisms (SNPs), relevant for mental disease-related, quantifiable behavioral phenotypes. Here we propose an individual-based model to use genome-wide significant markers for extracting first genetic(More)
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