Tomoyuki Mochizuki

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PURPOSE A randomized clinical study was conducted to compare the outcome between double-bundle (DB) and single-bundle (SB) anterior cruciate ligament (ACL) reconstructions with 4-strand semitendinosus tendon (ST). METHODS We divided 68 patients with unilateral ACL injury into 2 groups according to their birth date, and they were followed up in person for(More)
PURPOSE The recently developed 2-bundle anterior cruciate ligament (ACL) reconstruction lacks sufficient anatomic background. The purpose of this anatomic study was to describe functional anteromedial (AM) and posterolateral (PL) portions of the natural ACL and to provide a reproducible description of the graft placement. Our hypothesis was that the core(More)
Mesenchymal stem cells (MSCs) can be obtained from various tissues, and contain common features. However, an increasing number of reports have described variant properties dependent of cell sources. We examined (1) whether MSCs existed in several intraarticular tissues, (2) whether gene expression profiles in intraarticular tissue MSCs closely resembled(More)
BACKGROUND It is generally believed that the supraspinatus is the most commonly involved tendon in rotator cuff tears. Clinically, however, atrophy of the infraspinatus muscle is frequently observed in patients with even small to medium-size rotator cuff tears. This fact cannot be fully explained by our current understanding of the anatomical insertions of(More)
The purpose of this study is to evaluate the morphology of the mid-substance and fan-like extension fibres of ACL during knee motion with reference to the femoral attachment. This study used six fresh-frozen cadaveric knees and 22 embalmed cadaveric knees to macroscopically evaluate morphological changes in the ACL attachment during knee motion. Three(More)
Detailed anatomical information of the infraspinatus is important in order to discuss muscle function. The aim of this study was to investigate the morphology, histology and innervation of the infraspinatus muscle, in order to construct an anatomical basis for diagnoses and operative procedures. We used 51 shoulders without rotator cuff tears of 27 Japanese(More)
OBJECTIVE Synovial mesenchymal stem cells (MSCs) are a promising cell source for cartilage regeneration due to their high chondrogenic potential. For clinical safety, autologous human serum should be used instead of fetal bovine serum (FBS). We undertook this study to compare the 2 types of serum for their enhancement of the proliferation and chondrogenic(More)
OBJECTIVE Mesenchymal stem cells from synovium have a greater proliferation and chondrogenic potential than do those from bone marrow, periosteum, fat, and muscle. This study was undertaken to compare fibrous synovium and adipose synovium (components of the synovium with subsynovium) to determine which is a more suitable source for mesenchymal stem cells,(More)
BACKGROUND Double-bundle anterior cruciate ligament (ACL) reconstruction has several potential advantages over single-bundle reconstruction with hamstring tendons. However, there are still controversies regarding tunnel placement in tibial and femoral attachments. HYPOTHESIS The macroscopically normal ACL consists of small bundles about 1 mm in diameter.(More)
INTRODUCTION Current cell therapy for cartilage regeneration requires invasive procedures, periosteal coverage and scaffold use. We have developed a novel transplantation method with synovial mesenchymal stem cells (MSCs) to adhere to the cartilage defect. METHODS For ex vivo analysis in rabbits, the cartilage defect was faced upward, filled with synovial(More)