Tomoya Tanaka

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Alzheimer's disease (AD) shows degeneration of the cholinergic system in the medial septum, thereby eliciting down-regulation of the olfactory function in patients. We have previously reported that olfactory bulbectomized (OBX) mice show hippocampus-dependent memory impairment as assessed by memory-related behavioral tasks and hippocampal long-term(More)
Sunifiram is a novel pyrrolidone nootropic drug structurally related to piracetam, which was developed for neurodegenerative disorder like Alzheimer's disease. Sunifiram is known to enhance cognitive function in some behavioral experiments such as Morris water maze task. To address question whether sunifiram affects N-methyl-D-aspartate receptor(More)
Continuous human monitoring is substantially useful to realize a high QoL (quality of life) society. In the previous work, we fabricated a prototype system for monitoring an electrocardiograph (ECG), heart rate (HR), 3 axes human body acceleration, temperature for human body and human circumstances, simultaneously. These data are transmitted to the host PC(More)
Adenosine triphosphate (ATP) not only functions as an energy-carrier substance and an informative molecule, but also acts as a marker substance in studies of both bio-traces and cellular/tissular viability. Due to the importance of the ATP function for living organisms, in situ assays of ATP are in demand in various fields, e.g., hygiene. In the present(More)
For maintaining our health, we need to know our physical condition. The daily monitoring which is one of methods for taking our physical condition is very important. Because we have to attach such a monitoring device on some part of our body for taking our condition, noninvasive monitoring devices are needed. For realizing such a noninvasive monitoring(More)
Understanding the dynamics with which a water droplet penetrates a pore is important because of its relationship with transfer phenomena in plants and animals. Using a high-speed camera, we observe the penetration processes of a water droplet into a cylindrical pore on a silicone substrate. The force on the water droplet is generated by dropping the(More)
The analysis of changes in the brain neurosteroid (NS) levels due to various stimuli can contribute to the elucidation of their physiological roles, and the discovery and development of new antipsychotic agents targeting neurosteroidogenesis. We developed methods for the differential and quantitative analyses of the brain levels of allopregnanolene (AP) and(More)