Tomoko Ishiya

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The PTEN/MMAC1 gene, located on human chromosome 10q23, has recently been implicated as a candidate tumor suppressor gene in human cancers. In the present study, 12 uterine cancer cell lines and 87 uterine cancers of various grades and histological type were analyzed for PTEN/MMAC1 gene. Three of 44 endometrial carcinoma (7%) showed no PTEN/MMAC1 mRNA(More)
PURPOSE To evaluate the efficacy and toxicity of combination chemotherapy with bleomycin, vincristine, mitomycin, and consecutive low-dose (CLD) administration of cisplatin (CLD-BOMP) for patients with recurrent cervical carcinoma. PATIENTS AND METHODS Ninety patients with recurrent cervical carcinoma and no prior chemotherapy were enrolled onto this(More)
The effect of storage temperature (0, 5, 10, and 15°C) and killing procedure (instant, struggled, temperature shocked, and spinal cord destruction killing) on post-mortem changes in the muscle of the horse mackerel caught near Nagasaki, Japan, was investigated. Temporal changes in adenosine triphosphate (ATP), inosine monophosphate (IMP), and lactic acid(More)
47 cases procedured for B anastomosis were yearly observed, because of simple tecnique with lower mortality, with the results that the post-operative complaints were on the decrease in three years after operation. Although this tecnique with 13 anastomosis is excellent, it is not yet satisfactory in respects of esophagitis. It was revealed that the(More)
tion were done. High incidence of bilirubin stones is observed in aged cases and as four t imes more in male than female. In 50% of cholesterol stone cases, 37% of bilirubin stone cases and 55% of other cases, well contrasted shadows are observed in a series of radiographic cholangiography. The bacteriological cultures which are taken from bile and internal(More)
named Component I, II and III. The former was found to be the major mucopolysaccharide in white bile having slower mobility than hyaluronic acid and was present in all white bile samples examined. In contrast , Component II and III were by far the minor components and were absent in half of the white bile samples. Component II had similar mobility to(More)
5593 Background: To evaluate the sensitivety, specificity, and accuracy of PET-CT for detecting lymph node metastasis in gynecologic carcinoma. METHODS Between May 2007 to August 2008, 36 consecutive patients (pts) with cervical carcinoma, endometrial carcinoma and epithelial ovarian carcinoma were enrolled. All pts underwent PET-CT prior to the surgery(More)
Serum Triglycerides level in hepatic disease showed high in serum hepatit is and obstructive jaundice, relatively high level in viral hepatitis, and relatively low level in liver cirrhosis. In the course of hepatic disease, Triglycerides showed markedly relat ionship wi th liver functions, and especially S-GOT, S-GPT, bilirubin became normal or marked(More)
The resul t s : 1) The amount of cholesterol was significantly higher in the age group from 40 to 59 years old than tha t in the age group from 20 to 39 years old, while bile acids and phospholipid were not. 2) The relat ion of the amount of cholesterol to the weight ra t io of total bile acids and phospholipid to cholesterol ( T B S + P L ) / C h ra t io(More)
BACKGROUND Although postoperative infections continue to be a major problem in gynecologic surgery, there is still no consensus on the efficacy of antibiotic prophylaxis. METHODS This prospective randomized trial was conducted to investigate the prevention of major operating site infections after nonlaparotomy surgery, with treatment regimens as follows:(More)