Tomoko Hamano

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L. T. Perelman,1 V. Backman,1 M. Wallace,2 G. Zonios,1 R. Manoharan,1 A. Nusrat,3 S. Shields,4 M. Seiler,4 C. Lima,1 T. Hamano,1 I. Itzkan,1 J. Van Dam,2 J. M. Crawford,5 and M. S. Feld1 1G. R. Harrison Spectroscopy Laboratory, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139 2Gastroenterology Division, Brigham and Women’s Hospital,(More)
During our careful survey of unregulated drugs from November 2011 to January 2012 in the Tokyo area, we found two new compounds in commercial products. The first was identified as the benzoylindole (2-iodophenyl)[1-(1-methylazepan-3-yl)-1H-indol-3-yl]methanone (2), which is the azepane isomer of AM-2233 (1). Compound 2 was isolated by silica gel column(More)
During our careful surveillance of unregulated drugs in January to February 2011, we found two new compounds used as adulterants in herbal products obtained via the Internet. These compounds were identified by liquid chromatography–mass spectrometry, gas chromatography-mass spectrometry, accurate mass spectrometry, and nuclear magnetic resonance(More)
During our continual surveillance of unregulated drugs in May–June 2011, we found two new compounds as adulterants in herbal products obtained at shops in the Tokyo area. These compounds were identified by liquid chromatography–mass spectrometry, gas chromatography–mass spectrometry, accurate mass spectrometry, and nuclear magnetic resonance spectroscopy.(More)
During our careful surveillance of unregulated drugs, we found five new compounds used as adulterants in herbal and drug-like products obtained via the Internet. These compounds were identified by liquid chromatography–mass spectrometry, gas chromatography–mass spectrometry, accurate mass spectrometry, and nuclear magnetic resonance spectroscopy. The first(More)
An air-injection press, which has holes punched in the heating plates, injects high-pressure air through the holes of one plate into particleboard and discharges the air through the other plate during press heating. The press can manufacture particleboard from high-moisture particles by controlling blowout of the boards. In this study, the optimum diameter(More)
An air-injection press (AIP) was developed to prevent accidental blowouts of boards during production. In this study, the effects of the AIP on preventing blowouts were investigated by artificially creating a blowout-prone condition, and the press was shown to be effective in preventing blowouts. The modulus of rupture of the boards was almost constant(More)
Juice and integument of leaves of 3 Aloe species, Aloe vera, A. ferox and A. africana, are not allowed to be used as food according to the Pharmaceutical Affairs Law in Japan. On the other hand, whole leaves of A. arborescens can be used as food. The present study was designed to distinguish Aloe species by random amplified polymorphic DNA (RAPD) analysis.(More)
An air-injection press, which has holes punched in the heating plates, injects high-pressure air through the holes of one plate into particleboards and discharges the air and vapor through the other plate during press heating. The press can manufacture particleboards from high-moisture particles by preventing blowouts of the boards. In this study, the(More)
A sildenafil-related compound was detected in a dietary supplement marketed as an aphrodisiac. The compound was detected during analysis of the dietary supplement using LC-UV and LC/electrospray ionization-MS. The structure of the compound was established using high resolution MS, NMR spectrometry, and X-ray crystal structure analysis. The compound was(More)
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