Tomofusa Yamauchi

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PURPOSE It has been shown that bradykinin (BK) protects retinal neurons against glutamate excitotoxicity, but it was not clear how BK inhibits glutamate excitotoxicity. The purpose of this study was to investigate the effect of opening the mitochondrial adenosine triphosphate (ATP)-sensitive potassium (Mit K (ATP)) channel on glutamate excitotoxicity and(More)
PURPOSE To compare the visual performance of multifocal intraocular lenses (IOLs) and monofocal IOLs made of the same material. METHODS The subjects included patients implanted with either Tecnis® monofocal IOLs (ZA9003 or ZCB00) or Tecnis® multifocal IOLs (ZMA00 or ZMB00) bilaterally. We conducted a retrospective study comparing the two types of IOLs.(More)
Previously, we showed that dopamine protects cultured retinal neurons from N-methyl-D-aspartate (NMDA) receptor mediated-glutamate excitotoxicity via dopamine D1 receptor. This study has demonstrated for the first time that nitric oxide synthase (NOS) plays a crucial role in dopamine-induced neuroprotection. Our patch clamp study has shown that dopamine(More)
PURPOSE To evaluate the repeatability of a new method of measurement of visual acuity by use of a psychometric function. METHODS The visual acuity of 15 healthy adults was measured by use of a psychometric function (PFVA) and by use of a conventional method using a decimal visual acuity chart (DeVA). We performed two tests. To evaluate intra-rater(More)
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