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In 2011 Shoenfeld and Agmon-Levin proposed a new syndrome as a way of grouping together a range of emerging autoimmune diseases with possible adjuvant-associated causes, Autoimmune/Auto-inflammatory Syndrome Induced by Adjuvants (ASIA). At present, there is no evidence to suggest that ASIA syndrome is a viable explanation for unusual autoimmune diseases.(More)
Although the diverse functions served by the nuclear factor-κB (NF-κB) pathway in virtually all cell types are typically employed to deal with stress responses, NF-κB transcription factors also play key roles in the development of hemopoietic cells. This review focuses on how NF-κB transcription factors control various aspects of thymic T-cell and myeloid(More)
Regulatory T cells (Tregs) are a subset of CD4 T cells that are key mediators of immune tolerance. Most Tregs develop in the thymus. In this review we summarise recent findings on the role of diverse signalling pathways and downstream transcription factors in thymic Treg development.
volume 17 number 7 JulY 2016 nature immunology transgenic mouse model with GC B cell‒specific expression of a tamoxifen-inducible transgene encoding Cre recombinase that allows fate mapping of GC B cell progeny1. With this elegant model, the authors study the development of memory B cells and investigate the molecular events that occur during this process.(More)
The following is a critical analysis of ten articles directly referenced by Ms Meryl Dorey in her reply of September 2009 on behalf of herself and her organisation, the AVN, to the complaint submitted by Mr Ken McCleod. All articles mentioned in this document are listed with their PubMed ID (PMID). This will make them easier to find, should any follow up be(More)
Dear Ms Evans, The following document details a worrying discovery made regarding where Ms Dorey, current president of the Australian Vaccination Network (AVN), sourced some of her references used in her reply to Mr Ken McLeod's initial complaint. Ms Dorey begins: " Below are just a few of the hundreds of references to peer-reviewed studies which(More)
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