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Regulatory T cells (Tregs) are a subset of CD4 T cells that are key mediators of immune tolerance. Most Tregs develop in the thymus. In this review we summarise recent findings on the role of diverse signalling pathways and downstream transcription factors in thymic Treg development.
The following is a critical analysis of ten articles directly referenced by Ms Meryl Dorey in her reply of September 2009 on behalf of herself and her organisation, the AVN, to the complaint submitted by Mr Ken McCleod. All articles mentioned in this document are listed with their PubMed ID (PMID). This will make them easier to find, should any follow up be… (More)