Tom Moritz

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A NISO Recommended Practice is a recommended "best practice" or "guideline" for methods, materials, or practices in order to give guidance to the user. Such documents usually represent a leading edge, exceptional model, or proven industry practice. All elements of Recommended Practices are discretionary and may be used as stated or modified by the user to(More)
Efficient transduction of reconstituting hematopoletic stem cells (HSC) is currently only possible by cocultivation of target cells directly on producer cell lines, a method not applicable to human gene therapy protocols. Our laboratory has previously shown adhesion of primitive hematopoletic stem and progenitor cells to the carboxy-terminal 30/35-kD(More)
Human cord blood (CB) contains large numbers of both committed and primitive hematopoietic progenitor cells and has been shown to have the capacity to reconstitute the lympho-hematopoietic system in transplant protocols. To investigate the potential usefulness of CB stem and progenitor cell populations to deliver new genetic material into the blood and(More)
BACKGROUND Data are the evidentiary basis for scientific hypotheses, analyses and publication, for policy formation and for decision-making. They are essential to the evaluation and testing of results by peer scientists both present and future. There is broad consensus in the scientific and conservation communities that data should be freely, openly(More)
The tumour protein D52 isoform 1 (PC-1), a member of the tumour protein D52 (TPD52) protein family, is androgen-regulated and prostate-specific expressed. Previous studies confirmed that PC-1 contributes to malignant progression in prostate cancer with an important role in castration-resistant stage. In the present work, we identified its impact in(More)
We are very pleased to announce that the winner of the Fifth Elsevier Chemometrics Award is Dr. Johan Trygg from the University of Umeå, Sweden. The Elsevier Chemometrics Award was established to stimulate the careers of young scientists (younger than 40 years) by rewarding noteworthy accomplishments in chemometrics. Winners of the previous awards were: Dr.(More)
When the shortage of qualified psychiatrists and other physicians in Ohio's mental institutions reached the critical point in 1975, a number of measures were implemented to upgrade medical manpower. Salaries were increased, and the leadership of the medical and psychiatric community was enlisted to help encourage physicians to enter public service. In(More)
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