Tom M. Walley

Learn More
OBJECTIVES To compare the clinical effectiveness of zaleplon, zolpidem or zopiclone (Z-drugs) with either benzodiazepines licensed and approved for use in the UK for the short-term management of insomnia (diazepam, loprazolam, lorazepam, lormetazepam, nitrazepam, temazepam) or with each other. METHODS MEDLINE, EMBASE, PsycINFO, Science Citation Index/Web(More)
BACKGROUND A 2003 survey suggested the number of noncommercial trials in the UK was declining. Formation of the NIHR in 2006 and increased research spending by the Department of Health may have increased the number of noncommercial trials but no data are available. METHODS Available data on UK noncommercial trials (were obtained from the two relevant(More)
BACKGROUND Alcohol dependence affects approximately 3% of the English population, and accounts for significant medical and psychiatric morbidity. Only 5.6% of alcohol-dependent individuals ever access specialist treatment and only a small percentage ever seek treatment. As people who are alcohol dependent are more likely to have experienced health problems(More)
A low-jitter charge-pump PLL is built in 90-nm CMOS for 1–10 Gb/s SerDes transmitter clocking. The PLL employs a programma-ble dual-path loop filter with integrating path and novel resistorless proportional path that can be independently controlled and accurately modeled for flexible setting of closed-loop bandwidth and peaking. Frequency is synthesized(More)
  • 1