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BACKGROUND Underweight and overweight may affect reproduction and interfere with treatment of infertility. The purpose of this report is to describe the independent effect of body weight on treatment with IVF and ICSI. METHODS Records of 5019 IVF or ICSI treatments in 2660 couples were reviewed. The influence of body mass index (BMI) on treatment outcome(More)
BACKGROUND Pregnancies conceived by assisted reproductive technology (ART) are at increased risk of adverse outcomes. Previous studies have suggested increased placental weight and increased placental weight/birthweight ratio in pregnancies associated with adverse outcomes. We therefore studied the association of ART with placental weight and placental(More)
Between 2.1% and 4.2% of all children born in Scandinavian countries are conceived with the help of assisted reproductive technology. The present study is one of the first to have followed up infertile women over a long period. Data on outcomes, satisfaction and the perceived consequences of IVF treatment were collected by means of a questionnaire among a(More)
There is increased risk of early pregnancy loss after assisted reproduction. In this study the use of serum human chorionic gonadotrophin (HCG) concentrations on day 12 after in-vitro fertilization (IVF) and embryo transfer was evaluated to predict pregnancy outcome. A total of 417 IVF pregnancies were included. Early pregnancy loss was defined as(More)
STUDY QUESTION Have changes in culture media used for IVF resulted in changes in offspring birthweight or placental weight that differed from the trends in offspring from spontaneous conceptions during the corresponding time periods? SUMMARY ANSWER Changes in culture media used for IVF were associated with significant differences in offspring birthweight(More)
the last 25 years, methods of in vitro fertilization (IVF) have become available for most categories of infertile couples. In 1988, Lanzendorf et al. reported an experiment with intracytoplasmic sperm injection (ICSI) on human oocytes, 1 and in 1992, ICSI was presented as a successful method of treatment for certain types of male infertility. 2 The ICSI(More)
OBJECTIVE To investigate the effect of advanced maternal age (AMA) separately in nulliparous and multiparous women on obstetric and perinatal outcomes in singleton gestations. STUDY DESIGN A historical cohort study on data from 6,619 singleton pregnancies between 2004 and May 2007 was performed. AMA was defined as 35 years and older. Obstetric and(More)
BACKGROUND Down-regulation with GnRH agonist has been suggested to result in a profound suppression of LH bioactivity, reduced estradiol synthesis, and thus impaired IVF and pregnancy outcome. The aims of this study were: (i) to assess the usefulness of serum LH measurement on stimulation day 1 as a predictor of ovarian response, conception and pregnancy(More)
STUDY QUESTION Are low serum concentrations of human chorionic gonadotrophin (hCG) in very early pregnancy associated with pre-eclampsia risk? SUMMARY ANSWER Low hCG concentrations in very early pregnancy are associated with increased risk of severe pre-eclampsia. WHAT IS KNOWN ALREADY Low maternal serum concentrations of hCG early in pregnancy may(More)
STUDY QUESTION Is unilateral oophorectomy associated with age at menopause? SUMMARY ANSWER Women who had undergone unilateral oophorectomy entered menopause 1 year earlier than women with two ovaries intact. WHAT IS ALREADY KNOWN There is substantial variation in age at natural menopause. Unilateral oophorectomy implies a significant reduction of the(More)