One of the earliest manifestations of diabetic neuropathy is denervation of the cardiovascular system; loss of heart rate variability may have a prevalence as high as 21.5% in diabetic patients, and declines at 1 beat/min/year, which is 3 times faster than in normal subjects. The cause of this neuropathy is unknown: attempts at decreasing the excess… (More)
This paper describes the implementation and performance of SPRINT, an interactive system for printed circuit board design developed at the Stanford Linear Accelerator Center (SLAC). Topics discussed include the placement subsystem, the routing subsystem consisting of an interactive manual router, an automatic batch router, and a via elimination program, as… (More)
Baroreflex sensitivity was measured in a group of diabetic patients from the slope of the regression of pulse interval on systolic arterial pressure, during elevation of pressure induced by phenylephrine. The response to Valsalva's manoeuvre was assessed in the same subjects. There was a good correlation between the two tests in the identification of… (More)
BACKGROUND Cardiac output (CO) is an important determinant of the hemodynamic state in patients with congestive heart failure (CHF). We tested the hypothesis that CO can be estimated from the right ventricular (RV) pressure waveform in CHF patients using a pulse contour cardiac output algorithm that considers constant but patient specific RV outflow tract… (More)
This paper describes an interactive system for editing of printed circuit layout designs. Each editing operation is dynamically checked against a set of user-defined design rules to assure that the resulting design is valid.