Tomá Kuba

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The presence of non-NMDA glutamate receptors in the rat sympathetic and parasympathetic ganglia was examined by immunocytochemistry using specific antibodies against AMPA-type excitatory amino acid receptor subunits (GluR1-4). Three kinds of antibodies specific to the GluR1, GluR2 and 3, and GluR4 subunits were used. The superior cervical ganglion and(More)
Tarsal tunnel syndrome (TTS) is a rare compression neuropathy of the posterior tibial nerve. Typical symptoms are burning pain and paresthesia in the toes and along the sole of the foot. The presence of Tinel's sign and objective sensory loss in the territory of any of the terminal branches of the posterior tibial nerve are diagnostically helpful. The(More)
The Cornell et al. empirical potential (Cornell et al., J Am Chem Soc 1995, 117, 5197) was modified by the introduction of nonplanarity of the amino group in guanine, adenine, and cytosine. Reparameterization was performed for 12 bond parameters of the amino group (three valence angles (C-N-H(1), C-N-H(2), and H(1)-N-H(2)) and the improper dihedral angle at(More)
In eight patients with unilateral pontine and midbrain lesions, brainstem auditory evoked potentials (BAEPs) were studied with ipsilateral (Cz-Ai) and contralateral (Cz-Ac) recordings after monaural stimulation. In all cases, the most prominent abnormality was noted in BAEP generated by stimulating the ear ipsilateral to the lesions. The Cz-Ai and Cz-Ac(More)
Photochromic ligands (PCLs), defined as photoswitchable molecules that are able to endow native receptors with a sensitivity towards light, have become a promising photopharmacological tool for various applications in biology. In general, PCLs consist of a ligand of the target receptor covalently linked to an azobenzene, which can be reversibly switched(More)
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