Tokutaro Tanaka

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Although several risk factors for stroke have been identified, one-third remain unexplained. Here we show that infection with Streptococcus mutans expressing collagen-binding protein (CBP) is a potential risk factor for haemorrhagic stroke. Infection with serotype k S. mutans, but not a standard strain, aggravates cerebral haemorrhage in mice. Serotype k S.(More)
Specific areas of cortical activity during solid bolus swallowing in humans are unknown. We tested the hypothesis that cortical representations of swallowing in humans may vary by bolus type. Twenty-one normal subjects swallowed three kinds of food: agar (solid), a capsule and water. We followed the same countdown method for identification of the cortical(More)
We present a rare case of an acute epidural hematoma extending through a skull fracture into a cephalohematoma in a neonate. The epidural hematoma was caused by a fall after delivery. The neonate remained neurologically asymptomatic. A computed tomography scan 12 days after delivery showed the large-volume epidural hematoma with midline shift. We performed(More)
Lamotrigine (LTG) has been recognized as one of the best newer antiepileptic drugs (AEDs) used in developed countries since 1991. A retrospective study was carried out to evaluate the efficacy, adverse reactions, and other peculiarities of LTG. Two hundred and eighty-one patients with epilepsy, aged 16 or more, were treated with LTG between December 2008(More)
In this retrospective study, we evaluated the safety and efficacy of levetiracetam (LEV) as an antiepileptic drug by using data in our hospital database from October 2010, when LEV became available in Japan, through August 2011. Data from patients aged 16 years or more (n=132) with localization-related epilepsy (n=112) and generalized epilepsy (n=19) were(More)
bolus swallowing in humans are unknown. We tested the hypothesis that cortical representations of swallowing in humans may vary by bolus type. Twenty-one normal subjects swallowed three kinds of food: agar (solid), a capsule and water. We followed the same countdown method for identification of the cortical representations during swallowing performances as(More)
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