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  • Anton Bolotinsky, Arthur Breitman, +35 authors Vlad Zamfir
  • 2015
Unless stated otherwise, the views expressed within this report are mine alone and quotes and/or citations herein are not endorsements of this report by the individuals above or organizations they represent. Financial disclosure: this research was self-funded and conducted as part of a continual effort to understand the fluid landscape involving the(More)
Videothoracoscopic stapled diverticulectomy with distal esophageal myotomy and partial fundoplasty was successfully done for a 65-year-old woman who had a large, symptomatic epiphrenic diverticulum associated with achalasia. This minimally invasive approach resulted in good symptomatic relief of dysphagia, minimal postoperative pain, a 1-day hospital stay,(More)
Hematologic characteristics of 36 Greyhounds were studied and compared with characteristics of 22 non-Greyhound controls. Fourteen of the Greyhounds were tested and found to be seronegative for Ehrlichia canis and Babesia canis. Compared with the non-Greyhounds, Greyhounds had higher mean hemoglobin concentration, PCV, mean corpuscular volume, and mean(More)
Abnormal organization of platelet microtubules is associated with abnormal platelet formation in hereditary macrothrombocytopenias such as the gray platelet syndrome, May-Hegglin anomaly, and Epstein's syndrome, and that of the Wistar Furth rat, suggesting that aberrant microtubule organization may contribute to defective platelet formation in these(More)
An assay describing conditions for the maturation of single immature megakaryocytes in vitro is reported. Enriched populations of small, relatively immature megakaryocytes have been found to develop into single, mature megakaryocytes by 60 hours in semisolid agar cultures. Continued incubation of these cells did not lead to the formation of colonies within(More)
A thrombocytopoiesis-stimulating factor (TSF or thrombopoietin) from kidney cell culture medium was injected into mice, and the number and size of megakaryocytes in the bone marrow were determined. For controls, other mice were injected with saline, normal rabbit serum (NRS), or rabbit anti-mouse platelet serum (RAMPS). Both TSF and RAMPS caused significant(More)
Both large, acute doses of erythropoietin (EPO) and short-term hypoxia increase platelet counts in mice, but long-term hypoxia causes thrombocytopenia. Therefore, we tested the hypothesis that EPO injected in large, chronic doses (a total of 80 U of EPO over a 7-day period) might cause thrombocytopenia. EPO caused increased red blood cell (RBC) production,(More)
BACKGROUND & AIMS To investigate the peripheral sensory effects of repeated stress in patients with postinfectious irritable bowel syndrome (IBS), we tested whether stress following self-limiting bacterial colitis increases colonic dorsal root ganglia (DRG) nociceptive signaling. METHODS C57BL/6 mice were infected with Citrobacter rodentium. Stress was(More)