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A cyclopentenone prostaglandin activates mesangial MAP kinase independently of PPARgamma.
The mitogen-activated protein (MAP) kinases mediate the response of renal glomerular mesangial cells to a variety of physiologic and pathologic stimuli. This investigation examines the effect of theExpand
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15-Deoxy-Delta12,14-prostaglandin J2 regulates mesangial cell proliferation and death.
BACKGROUND Proliferation of intrinsic glomerular cells is a common response to renal injury. Acutely, proliferation may be beneficial, but sustained glomerular hypercellularity after injury isExpand
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