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Monitoring urban land use requires very high spatial resolution image data, acquired either by airborne or spaceborne sensor systems. The information content of such images is very complex, thus information extraction is currently performed on the basis of visual interpretation. The aim of the research described in this study is to formalise the visual… (More)
UNLABELLED Focal amplification and activating point mutation of the MET gene are well-characterized oncogenic drivers that confer susceptibility to targeted MET inhibitors. Recurrent somatic splice site alterations at MET exon 14 (METex14) that result in exon skipping and MET activation have been characterized, but their full diversity and prevalence across… (More)
INTRODUCTION Chromosomal rearrangements involving neurotrophic tyrosine kinase 1 (NTRK1) occur in a subset of non-small cell lung cancers (NSCLCs) and other solid tumor malignancies, leading to expression of an oncogenic TrkA fusion protein. Entrectinib (RXDX-101) is an orally available tyrosine kinase inhibitor, including TrkA. We sought to determine the… (More)
MELANOMA BRIDGE 2015 KEYNOTE SPEAKER PRESENTATIONS Molecular and immuno-advances K1 Immunologic and metabolic consequences of PI3K/AKT/mTOR activation in melanoma Vashisht G. Y. Nanda, Weiyi Peng, Patrick Hwu, Michael A. Davies K2 Non-mutational adaptive changes in melanoma cells exposed to BRAF and MEK inhibitors help the establishment of drug resistance… (More)
From this SOI expertise, we have designed, developed, and fabricated a number of novel devices that exploit a variety of mechanical, electrical, and optical phenomena, including atomic-physics based devices. We present a high-level description of our SOI process technologies using product examples. Of particular note are a novel accelerometer, RF MEMS… (More)
The paper deals with the transformation of an interpretation key, established for a visual interpretation, into a rule base applied for automated image analysis. An object-based approach is used for that purpose. The methodology is demonstrated for the detection of coca fields on medium resolution satellite imagery. The monitoring of illicit coca… (More)
Physical unclonable functions (PUFs) make use of the measurable intrinsic randomness of physical systems to establish signatures for those systems. PUFs provide a means to generate unique keys that don't need to be stored in nonvolatile memory, and they offer exciting opportunities for new authentication and supply chain security technologies.