Toby Batten

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Fast inhibitory synaptic transmission in the brain relies on ionotropic GABA(A) receptors (GABA(A)R). Eighteen genes code for GABA(A)R subunits, but little is known about the epsilon subunit. Our aim was to identify the synaptic transmission properties displayed by native receptors incorporating epsilon. Immunogold localization detected epsilon at synaptic(More)
INTRODUCTION : Broad-spectrum grass pollen immunotherapies contain large numbers of allergenic proteins from multiple species. The principle of homologous grouping is used as a tool to assist in the standardization of allergen immunotherapy. This study reviews the principle of homologous grouping, questions what an exemplar grass should be, and queries(More)
11 12 Belujon, P.*, Baufreton, J.*, Grandoso, L., Boué-Grabot, E*., Batten, T.F.C. ., Ugedo, L., 13 Garret, M.*° and Taupignon A. I.* 14 15 16 17 * University Bordeaux2, CNRS UMR 5227, Bordeaux, France 18 + Department of Pharmacology, School of Medicine, University of the Basque Country, 19 Vizcaya, Spain § Leeds Institute of Genetics, Therapeutics and(More)
BACKGROUND Our knowledge of allergen structure and function continues to rise and new scientific data on the homology and cross-reactivity of allergen sources should be considered to extend the work of Lorenz et al., 2009 (Int Arch Allergy Immunol. 148(1):1-1, 2009) and the concept of homologous groups. In addition to this, sophisticated techniques such as(More)
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