Tobias Wiedemann

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Infection with Helicobacter pylori, carrying a functional cag type IV secretion system (cag-T4SS) to inject the Cytotoxin associated antigen (CagA) into gastric cells, is associated with an increased risk for severe gastric diseases in humans. Here we studied the pathomechanism of H. pylori and the role of the cag-pathogenicity island (cag-PAI) for the(More)
BACKGROUND Gastrointestinal (GI) inflammation in mice and men are frequently accompanied by distinct changes of the GI microbiota composition at sites of inflammation. Helicobacter (H.) pylori infection results in gastric immunopathology accompanied by colonization of stomachs with bacterial species, which are usually restricted to the lower intestine.(More)
Cassidian Electronics, a globally operating business unit of EADS, aimed to implement a collaborative portal for its quality management department. After conducting a successful pilot phase producing a prototype for a small number of users it soon became apparent that a large scale roll-out would not be feasible without proper methodological support. As no(More)
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