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ESCAschool study: trial protocol of an adaptive treatment approach for school-age children with ADHD including two randomised trials
BackgroundThe ESCAschool study addresses the treatment of school-age children with attention-deficit/hyperactivity disorder (ADHD) in a large multicentre trial. It aims to investigate threeExpand
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Policy entrepreneurs in international river basins—getting climate adaptation on the cross-border water policy agenda
In this study, we look at the role which water policy entrepreneurs play in promoting and stimulating climate adaptation measures in international river basins. In a Dutch-German case study in theExpand
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Pilot study on HTR2A promoter polymorphism, −1438G/A (rs6311) and a nearby copy number variation showed association with onset and severity in early onset obsessive–compulsive disorder
A previous study showed that a single nucleotide polymorphism (SNP), −1438G/A (rs6311), found in the transcriptional control region of the gene that encodes the serotonin-receptor 2A (HTR2A) wasExpand
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Who Wants to Become a Child Psychiatrist? Lessons for Future Recruitment Strategies From a Student Survey at Seven German Medical Schools
ObjectiveThe objective of this survey was to investigate undergraduate German medical students’ attitudes toward child and adolescent psychiatry (CAP) and to describe the characteristics of studentsExpand
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DCLK1 Variants Are Associated across Schizophrenia and Attention Deficit/Hyperactivity Disorder
Doublecortin and calmodulin like kinase 1 (DCLK1) is implicated in synaptic plasticity and neurodevelopment. Genetic variants in DCLK1 are associated with cognitive traits, specifically verbal memoryExpand
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Acetylcholine-metabolizing butyrylcholinesterase (BCHE) copy number and single nucleotide polymorphisms and their role in attention-deficit/hyperactivity syndrome.
A previous genome-wide screen for copy number variations (CNVs) in attention deficit/hyperactivity disorder (ADHD) revealed a de novo chromosome 3q26.1 deletion in one of the patients. CandidateExpand
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PPP2R2C as a candidate gene of a temperament and character trait-based endophenotype of ADHD
There are several lines of evidence that the 4p16 region is a candidate locus of both attention-deficit/hyperactivity disorder (ADHD) and bipolar disorder. None of the harbored candidate genes ofExpand
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Individualised short-term therapy for adolescents impaired by attention-deficit/hyperactivity disorder despite previous routine care treatment (ESCAadol)—Study protocol of a randomised controlled
BackgroundDespite the high persistence rate of attention-deficit/hyperactivity disorder (ADHD) throughout the lifespan, there is a considerable gap in knowledge regarding effective treatmentExpand
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Toward a Dimensional Assessment of Externalizing Disorders in Children: Reliability and Validity of a Semi-Structured Parent Interview
Objective This study assesses the reliability and validity of the DSM-5-based, semi-structured Clinical Parent Interview for Externalizing Disorders in Children and Adolescents (ILF-EXTERNAL). MethodExpand