Tobias Mayer

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Chidamber and Kemerer (C&K) outlined some initial proposals for language-independent OO design metrics in 1991. This suite is expanded on by C&K in 1994 and the metrics were tested on systems developed in C++ and Smalltalk™. The six metrics making up the C&K suite can be criticised for a number of reasons. This does not make them bad metrics; on the(More)
Microgravity induces changes in the cytoskeleton. This might have an impact on cells and organs of humans in space. Unfortunately, studies of cytoskeletal changes in microgravity reported so far are obligatorily based on the analysis of fixed cells exposed to microgravity during a parabolic flight campaign (PFC). This study focuses on the development of a(More)
—The recently finalized High-Efficiency Video Coding (HEVC) standard was jointly developed by the ITU-T Video Coding Experts Group (VCEG) and the ISO/IEC Moving Picture Experts Group (MPEG) to improve the compression performance of current video coding standards by 50%. Especially when it comes to transmit high resolution video like 4K over the internet or(More)
OBJECTIVE The generation of acinar and ductal cells from human pluripotent stem cells (PSCs) is a poorly studied process, although various diseases arise from this compartment. DESIGN We designed a straightforward approach to direct human PSCs towards pancreatic organoids resembling acinar and ductal progeny. RESULTS Extensive phenotyping of the(More)
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