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—In this paper a novel system for automatic detection and segmentation of focal liver lesions in CT images is presented. It utilizes a probabilistic boosting tree to classify points in the liver as either lesion or parenchyma, thus providing both detection and segmentation of the lesions at the same time and fully automatically. To make the segmentation(More)
For patients with keratoconus, rigid gas-permeable contact lenses are the first line correction method and allow good visual acuity for quite some time. In severe stages of the disease with major cone-shaped protrusion of the cornea, even specially designed keratoconus contact lenses are no longer tolerated. If there are contraindications for intrastromal(More)
During the last 20 years, biologicals have become increasingly relevant in oncologic therapy. Depending on the medication used, there are different profiles of ocular side effects. Although these can be present in up to 70% of patients, they are generally underreported in the literature. Therefore, the pathophysiological details of their development are(More)
Wir berichten über einen einzigartigen Fall eines jungen Patienten, der bei Keratokonus vor 20 Jahren eine perforierende Keratoplastik erhalten hatte und sich in unserer Klinik mit Visusverschlechterung bei Salzmann’scher nodulärer Degeneration auf dem Transplantat, wahrscheinlich aufgrund einer rezidivierenden Herpeskeratitis, vorstellte. Der Patient wurde(More)
Unter Therapie mit Tamoxifen tritt bei 0,6–12% der behandelten Patienten eine Schädigung okulärer Strukturen auf. Diese zeichnet sich klassischerweise durch einen ausgeprägten Visusverlust bei kristallinen glitzernden Einlagerungen in die Makula mit Makulaödem oder durch kristalline Einlagerungen in die periphere Retina aus. Wir berichten über eine(More)
Acanthamoeba keratitis is rare, but difficult to treat. Penetrating keratoplasty is performed in therapy-resistant cases. Nevertheless, subsequent recurrences occur in 40 % of the cases. In addition to triple-topical therapy (polyhexamid, propamidinisoethionat, neomycin), treatment alternatives are corneal cryotherapy and/or crosslinking (CXL). The aim of(More)
Purpose. To assess the intraoperative results comparing two non-mechanical laser assisted penetrating keratoplasty approaches in keratoconus and Fuchs dystrophy. Patients and Methods. 68 patients (age 18 to 87 years) with keratoconus or Fuchs dystrophy were randomly distributed to 4 groups. 35 eyes with keratoconus and 33 eyes with Fuchs dystrophy were(More)
Acanthameoba keratitis is a serious ophthalmological condition with a potentially vision-threatening prognosis. Early diagnosis and recognition of relapse, and the detection of persistent Acanthamoeba cysts, are essential for informing the prognosis and managing the condition. We suggest the use of in vivo confocal microscopy not only to identify the early(More)
BACKGROUND Penetrating keratoplasty (PKP) in children is associated with specific age-related problems. In contrast to adults, children can be examined less easily and they are not readily complaining about symptoms. Thus, the rate of intra- and postoperative complications is higher than in adults. In addition, amblyopia is a major issue before the age of(More)
Ein 49-jähriger Patient stellte sich zur Mitbeurteilung in unserer neuroophthalmologischen Sprechstunde vor. Er klagte über Metamorphopsien und Visusreduktion, die am linken Auge (LA) stärker als am rechten Auge (RA) ausgeprägt seien. Zudem bestünden zunehmende Beschwerden beim Lesen. Seine Mutter habe eine nicht genauer definierte Sehstörung, bei seiner(More)