Tobias Hager

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—In this paper a novel system for automatic detection and segmentation of focal liver lesions in CT images is presented. It utilizes a probabilistic boosting tree to classify points in the liver as either lesion or parenchyma, thus providing both detection and segmentation of the lesions at the same time and fully automatically. To make the segmentation(More)
BACKGROUND In approximately 0.6-12% of patients systemic tamoxifen therapy is complicated by ocular toxicity. Classical findings include severe loss of visual acuity combined with crystalline retinal deposits in the macula and macular edema or crystalline deposits in the peripheral retina. METHODS We report the case of a 55-year-old female patient with(More)
During the last 20 years, biologicals have become increasingly relevant in oncologic therapy. Depending on the medication used, there are different profiles of ocular side effects. Although these can be present in up to 70% of patients, they are generally underreported in the literature. Therefore, the pathophysiological details of their development are(More)
Introduction Behavioral phenotyping is indispensible for biomedical research. Fear conditioning has been one of the most successful behavior assays in behavioral neuroscience, to investigate the neural systems and molecular basis of various aspects of emotional learning across a wide range of species [1]. Dysfunction of the fear circuits is assumed to(More)
INTRODUCTION We report a unique case of a young patient who underwent penetrating keratoplasty for keratoconus 20 years previously and presented in our department with visual deterioration due to Salzmann's nodular degeneration (SND) on the corneal graft, induced probably by underlying recurrent herpetic (HSV) keratitis. The patient was treated with(More)
Acanthameoba keratitis is a serious ophthalmological condition with a potentially vision-threatening prognosis. Early diagnosis and recognition of relapse, and the detection of persistent acanthamoeba cysts, are essential for informing the prognosis and managing the condition. We suggest the use of in-vivo confocal microscopy not only to identify the early(More)
BACKGROUND Waardenburg syndrome (WS) is a rare disease characterized by a sensorineural hearing loss and pigment anomalies of the iris, skin and hair due to mutations in PAX3. WS can be subdivided into four groups according to major and minor clinical signs. CASE REPORT We report the case of a 2 1/2-year-old coloured patient who presented in our(More)
This paper presents a meeting diarization system that estimates who spoke when in a meeting, especially if there is a speaker position change. Our previous system utilized solely the direction of arrival (DOA) information for meeting diarization. Therefore, when someone moves from one place to another, our previous system mistakes the utterances from second(More)
Acanthamoeba keratitis is rare, but difficult to treat. Penetrating keratoplasty is performed in therapy-resistant cases. Nevertheless, subsequent recurrences occur in 40 % of the cases. In addition to triple-topical therapy (polyhexamid, propamidinisoethionat, neomycin), treatment alternatives are corneal cryotherapy and/or crosslinking (CXL). The aim of(More)