Tobias Haenel

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BACKGROUND As antitumoral immunity requires the generation of local immunity directed against tissue proteins, we attempted to recreate within tumors the same environment found within tissues affected by autoimmune diseases (i.e., prolonged cytokine expression). Vaccinia virus (VV) has not been widely used as a cytokine gene therapy vector because of(More)
In the induction of tissue-directed immune responses, cytokines tend to be released within the affected tissues. We used two strategies to expose tumor tissues to continuous high levels of cytokines: First, a vaccinia interleukin (IL)2 recombinant was injected directly intratumorally 3-weekly at 10(7) pfus/dose in six patients with the solid tumor malignant(More)
Because of a depressive syndrome, a 39-year-old patient received 20 mg fluoxetine per day. Approximately 4 weeks later, treatment with this drug was stopped after the patient had complained of worsening tremor, particularly of the upper extremities. In addition, accommodation difficulties and problems with word-finding had appeared shortly before. The(More)
BACKGROUND Simian virus (SV) 40 sequences have been found in some, but not all studies of mesotheliomas. This virus is known to cause tumours in rodents but its role in human oncogenesis remains controversial. AIMS The aim of this study therefore was to determine whether SV40 is associated with the development of mesotheliomas in Australia. The absence of(More)
The investigation was aimed to assess pharyngeal sensitivity by means of intensity ratings and event-related potentials (ERPs) to mechanical stimulation. Twenty healthy subjects participated (14 female, mean age 23.6 years). Both intensity ratings and ERP were obtained in response to three intensities of mechanical stimuli (air puffs) applied to the nasal(More)
  • T Haenel
  • 1983
Before committing a suicidal act, many people consult a doctor because of somatic or functional complaints. Most of them do not express their suicidal thoughts, unless they are asked direct questions. The taking of a thorough history, possibly supplemented by information from relatives or friends, is the safest basis for an optimal assessment of the suicide(More)
Jakob Klaesi was born on the 29th May 1883 in Glarus Canton (Switzerland) and was assistant and later head physician at the Psychiatric University Hospital in Zurich, directed by Eugen Bleuler. Klaesi directed the new Psychiatric Outpatient Department in Basel from 1923 to 1926 and later founded the Schloss Kronau private clinic in the Zurich Canton. In(More)
  • T Haenel
  • 1984
The term psychogenic or reactive psychosis is used to describe a psychotic state which is experience-related and triggered by a precipitating event. Experimental studies have confirmed that under total sensory deprivation man responds by exhibiting psychotic reactions within a short time. Emotion psychoses, brief reactive psychoses are psychotic reactions(More)